Disopyramide/Class IB, II, and IV Antiarrhythmics Interactions
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Medical warning:
Very Serious. These medicines may interact and cause very harmful effects and are usually not taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
Disopyramide can affect your heart's rhythm. Other drugs can have the same effect.
What might happen:
Taking disopyramide with other agents that can affect your heart rhythm may increase your risk of an irregular heartbeat, which may be life-threatening.
What you should do about this interaction:
Make sure your healthcare professionals (e.g doctor or pharmacist) know that you are taking these medications together. Let your doctor know right away if you notice an irregular heartbeat or have any dizziness or fainting episodes. Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
- 1.Rythmodan (disopyramide) Australian prescribing information. Aventis Pharma Pty Ltd. September 22, 2000.
- 2.Calan (verapamil hydrochloride) US prescribing information. Pfizer, Inc. August, 2016.
- 3.Norpace (disopyramide phosphate) US prescribing information. Pfizer Inc. December, 2020.
Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.