Bromazepam/Strong CYP1A2 Inhibitors Interactions
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Medical warning:
Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
Your medicine may slow down how quickly your liver processes bromazepam.
What might happen:
Your blood levels of bromazepam may increase and cause harmful effects, including excessive sedation.
What you should do about this interaction:
Let your healthcare professional (e.g. doctor or pharmacist) know right away that you are taking these medicines together. Contact your doctor if you experience decreased coordination, excessive drowsiness, confusion, slurred speech, or difficulty breathing.Your healthcare professionals (e.g. doctor or pharmacist) may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
- 1.Apo-Bromazepam Canadian prescribing information. Apotex, Inc. March 10, 2016.
- 2.Lexotan (bromazepam) Australian prescribing information. Pharmaco (Australia) Ltd October 8, 2020.
- 3.Van Harten J, Holland RL, Wesnes K. Influence of multiple-dose administration of fluvoxamine on the pharmacokinetics of the benzodiazepinen bromazepam and lorazepam: a randomised, cross-over study. Eur Neuropsychopharmacol 1992 Sept;2(3):381.
- 4.This information is based on an extract from the Certara Drug Interaction Database (DIDB) Platform, Copyright Certara 1999-2023..
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.