COVID-19 Vaccines/Immunosuppressives; Immunomodulators Interactions

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

Some medicines may prevent your immune system from properly responding to the COVID-19 vaccine.

What might happen:

There is a chance that the vaccine may not prevent COVID-19 infection. There have been no specific studies to address this possible risk.

What you should do about this interaction:

Let your healthcare professionals (e.g. doctor or pharmacist) know that you are taking these medicines together. Your healthcare provider may want to delay administration of your medicine as a precaution.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

  • 1.Curtis JR, Johnson SR, Anthony DD, Arasaratnam RJ, Baden LR, Bass AR, etal. American College of Rheumatology COVID-19 Vaccine Clinical Guidance Summary for Patients with Rheumatic and Musucloskeletal Diseases - Version 5. Arthritis and Rheumatology. Available at: https://www.rheumatology.org/Portals/0/Files/COVID-19-Vaccine-Clinical-Gui dance-Rheumatic-Diseases-Summary.pdf February 2, 2022.
  • 2.Centers for Disease Control and Prevention (CDC). Interim Clinical Considerations for Use of COVID-19 Vaccines Currently Approved or Authorized in the United States. Accessed at: https://www.cdc.gov/vaccines/covid-19/clinical-considerations/covid-19-vac cines-us.html Last updated: September 15, 2023.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.