Epinephrine/Non-Cardioselective Beta-Blockers Interactions

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

Beta-blockers may block the effects of epinephrine.

What might happen:

Taking beta-blockers with epinephrine may cause your blood pressure to be increased. Your heart rate may slow down.The effect of epinephrine on severe allergic reactions may be decreased if you are also taking beta-blockers.

What you should do about this interaction:

Avoid taking these medications together. If they are taken together, your blood pressure and heart rate should be closely monitored. If you carry epinephrine as a precaution against allergic reactions, discuss the fact that you are also taking a beta-blocker with your doctor and what to do in the event of an emergency situation.Your healthcare professionals (e.g. doctor or pharmacist) may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

View Reference
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