Depo-Provera Vial Contraceptives Side Effects by Likelihood and Severity

COMMON side effects


If experienced, these tend to have a Less Severe expression

  • A Problem With Menstrual Periods
  • Abnormal Bleeding From The Uterus
  • Altered Interest In Having Sexual Intercourse
  • Dizziness
  • Headache
  • Intense Abdominal Pain
  • Nervousness
  • Reactions At The Site Of The Injection
  • Weight Gain

INFREQUENT side effects


If experienced, these tend to have a Severe expression

  • Depression

If experienced, these tend to have a Less Severe expression

  • A Skin Rash
  • Abdominal Bloating
  • Acne
  • Backache
  • Breast Pain
  • Chest Pain
  • Constipation
  • Decreased Appetite
  • Difficult Or Painful Urination
  • Difficulty Sleeping
  • Discharge Of Fluid From The Cervix
  • Drug-Induced Hot Flashes
  • Eye Pain
  • Fast Heartbeat
  • Generalized Weakness
  • Hair Loss
  • Inflammation Or Infection Of The Vagina
  • Joint Pain
  • Leg Cramps
  • Low Energy
  • Nausea
  • Pain In The Arms Or Legs
  • Pain With Menstruation
  • Trouble Breathing
  • Urinary Tract Infection
  • Vaginal Discharge
  • Visible Water Retention
  • Vomiting

RARE side effects


If experienced, these tend to have a Severe expression

  • A Blockage Of The Bile Duct That Resulting In High Bilirubin Levels
  • A Blood Clot In An Artery
  • A Breast Tumor
  • A Broken Bone
  • A Clot In The Lung
  • A Clot In The Small Veins That Carry Blood To Or From The Retina Of The Eye
  • A Hormone Disorder Where The Body Produces High Levels Of Cortisol Called Cushing's Syndrome
  • A Significant Type Of Allergic Reaction Called Anaphylaxis
  • A Type Of Allergic Reaction Called Angioedema
  • A Yellowing Of The Eyes Or Skin From Buildup Of Bilirubin Called Jaundice
  • Anemia
  • Blood Clot In A Deep Vein Of The Extremities
  • Blood Coming From Anus
  • Breastmilk Production Not Associated With Childbirth Or Nursing
  • Decreased Calcification Or Density Of Bone
  • Erythema Multiforme, A Type Of Allergic Skin Reaction
  • Erythema Nodosum, A Skin Condition With Red And Painful Nodules
  • High Amount Of Calcium In The Blood
  • Obstruction Of A Blood Vessel By A Blood Clot
  • Optic Disk Edema
  • Osteoporosis, A Condition Of Weak Bones
  • Overgrowth Of The Uterine Lining
  • Paralysis Of Nerves For The Face
  • Scleroderma, Hardening And Tightening Of The Skin And Connective Tissues
  • Seizures
  • Squamous Cell Carcinoma Of Cervix
  • Thrombophlebitis, An Inflamed Vein Due To A Blood Clot

If experienced, these tend to have a Less Severe expression

  • A Decrease In Production Of Breast Milk
  • A Feeling Of General Discomfort Called Malaise
  • A Feeling Of Pins And Needles On Skin
  • A Fibrous Thickening Of The Skin Called Induration
  • Abnormal Fat Distribution
  • Abnormal Glucose Tolerance Test Results
  • Absence Of Menstrual Periods
  • An Extreme Sense Of Wellbeing Called Euphoria
  • An Increased Interest In Having Sexual Intercourse
  • Body Odor
  • Changes In Appetite
  • Drowsiness
  • Dry Skin
  • Enlarged Superficial Veins
  • Excessive Thirst
  • Fever
  • Hirsutism, A Condition Of Hair Growth On Parts Of The Body Normally Without Hair
  • Hives
  • Hoarseness
  • Itching
  • Pain With Sexual Intercourse
  • Water Retention
  • Yellow-Brown Patches On Skin

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.