Talimogene laherparepvec/Acyclovir;Valacyclovir;Famciclovir Interactions

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

The cancer medicine injected into your tumor(s) contains a weakened herpes virus. Antiviral medicines used to treat herpes infections may counteract the effect of your cancer medicine.

What might happen:

The cancer medicine may not work as well.

What you should do about this interaction:

Before receiving talimogene laherparepvec injections, make sure your healthcare professionals (e.g. doctor or pharmacist) know that acyclovir, famciclovir or valacyclovir have been prescribed for you. Your provider may want to delay or discontinue one of your medicines.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

  • 1.Imlygic (talimogene laherparepvec) US prescribing information. Amgen Inc. October 27, 2015..

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.