Thyroid Preparations/Polystyrene Sulfonate Interactions
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Medical warning:
Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
Polystyrene sulfonate may bind to your thyroid hormone in your digestive tract, preventing your body from absorbing your medicine.
What might happen:
A decrease in the beneficial effects of your thyroid medicine may occur.
What you should do about this interaction:
Try to time your medicines so that you take your thyroid medicine at least 4 hours apart from polystyrene sulfonate.If you experience fatigue, sluggishness, constipation, stiffness, muscle cramps, loss of appetite, weight gain, dry skin, or difficulty in cold weather, contact your doctor.Your healthcare professionals (e.g. doctor or pharmacist) may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
- 1.Synthroid (levothyroxine sodium) US prescribing information. Abbott Laboratories February, 2024..
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.