Live Vaccines/Live Vaccines Interactions

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

Multiple live vaccines may be given on the same day; however, if they are not given on the same day, they should be given at least 4 weeks apart. Giving them sooner may prevent your immune system from reacting to the vaccine.

What might happen:

The second vaccine may not work as well.

What you should do about this interaction:

Make sure your healthcare professionals (e.g. doctor or pharmacist) know about any vaccinations you have recently received. Discuss the timing of your vaccines with your healthcare provider. You may need to reschedule your vaccination or repeat a vaccination in order to make sure it is effective.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

  • 1.Centers for Disease Control and Prevention. General Recommendations on Immunization. Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR. Available at: https://www.cdc.gov/vaccines/hcp/acip-recs/general-recs/index.html February 17, 2022;60(RR No.
  • 2):1-68.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.