Cefdinir/Oral Iron Interactions

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

Iron may bind with cefdinir in your stomach and intestines and prevent your body from absorbing cefdinir.

What might happen:

The amount of cefdinir in your blood may decrease and it may not work as well against your infection. The combination of cefdinir and iron may turn your stool a reddish color.

What you should do about this interaction:

If you are taking an iron supplement or a multivitamin containing iron, take your cefdinir at least 2 hours before or after the iron containing medicine. Let your healthcare professional (e.g. doctor or pharmacist) know if your infection does not seem to be getting better.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

  • 1.Omnicef (cefdinir) US prescribing information. Abbott Laboratories December, 2008.
  • 2.Ueno K, Tanaka K, Tsujimura K, Morishima Y, Iwashige H, Yamazaki K, Nakata I. Impairment of cefdinir absorption by iron ion. Clin Pharmacol Ther 1993 Nov;54(5):473-5.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.