Who should not take Co-Histine Expectorant Syrup?

The following conditions are contraindicated with this drug. Check with your physician if you have any of the following:

Conditions:

  • overactive thyroid gland
  • an inability to completely empty the bladder
  • enlarged prostate
  • severe disease of the arteries of the heart
  • significant uncontrolled high blood pressure
  • high blood pressure
  • diabetes
  • decreased kidney function
  • severe liver disease
  • closed angle glaucoma
  • pheochromocytoma
  • kidney disease with likely reduction in kidney function
  • systemic mastocytosis
  • untreated decreased level of thyroid hormones
  • decreased function of the adrenal gland
  • alcohol intoxication
  • cor pulmonale
  • low blood pressure
  • decreased lung function
  • constipation
  • acute inflammation of the pancreas
  • sleep apnea
  • CYP2D6 ultrarapid metabolizer
  • worsening chronic obstructive pulmonary disease
  • surgical removal of the adenoids in pediatric patient
  • drug abuse
  • asthma attack
  • blockage of the stomach or intestine
  • biliary and gallbladder problem
  • seizures
  • a condition where the body is unable to maintain adequate blood flow called shock
  • weakened patient
  • high pressure within the skull
  • CYP2D6 poor metabolizer
  • surgical removal of the tonsils in pediatric patient
  • history of opioid overdose
  • inherited dysfunction of autonomic nerve function
  • chronic kidney disease stage 5 (failure)

Allergies:

  • Guaifenesin
  • Opioids - Morphine Analogues
  • Tramadol
  • Sympathomimetic Agents
  • Ephedrine Analogues

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.