Who should not take Pazopanib 200 Mg Tablet Antineoplastic - Protein-Tyrosine Kinase Inhibitors?
The following conditions are contraindicated with this drug. Check with your physician if you have any of the following:
Conditions:
- diarrhea
- reduced UGT1A1 enzyme activity due to *28 polymorphism
- pancreatitis
- thrombotic thrombocytopenic purpura
- a type of blood disorder
- a hemorrhage in the brain
- acute thromboembolic stroke
- lung tissue problem
- a rupture in the wall of the stomach or intestine
- pregnancy
- impaired wound healing
- elevation of proteins in the urine
- recent operation
- bleeding of the stomach or intestines
- liver problems
- a gastrointestinal tract fistula
- bleeding
- obstruction of a blood vessel by a blood clot
- dissection of artery
- abnormal EKG with QT changes from birth
- left ventricular heart failure
- torsades de pointes
- a type of abnormal heart rhythm
- a heart attack
- significant uncontrolled high blood pressure
- hemolytic uremic syndrome
- a condition that affects the kidney and the blood
- low amount of potassium in the blood
- low amount of calcium in the blood
- low amount of magnesium in the blood
- a condition with low thyroid hormone levels
- prolonged QT interval on EKG
- a bad infection
- damage to the liver and inflammation
- high amount of bilirubin in the blood
- a localized weakening and ballooning in an artery wall called an arterial aneurysm
- abnormal liver function tests
- a patient who is producing milk and breastfeeding
- Child-Pugh class C liver impairment
- Child-Pugh class B liver impairment
Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.