Naproxen 500 Mg-Esomeprazole 20 Mg Tablet,Immediate And Delay Release Non-Steroidal Anti-Inflammatory (NSAID) Salicylates Side Effects by Likelihood and Severity

COMMON side effects


If experienced, these tend to have a Severe expression

  • A Skin Rash
  • Abnormal Liver Function Tests
  • Hives
  • Ringing In The Ears
  • Water Retention

If experienced, these tend to have a Less Severe expression

  • Constipation
  • Diarrhea
  • Dizziness
  • Drowsiness
  • Gas
  • Headache
  • Heartburn
  • Intense Abdominal Pain
  • Itching
  • Nausea
  • Reactions At The Site Of The Injection
  • Sensation Of Spinning Or Whirling
  • Visible Water Retention

INFREQUENT side effects


If experienced, these tend to have a Severe expression

  • A Change In Vision
  • Bleeding
  • Blurred Vision
  • Bruising
  • Bruising Under The Skin
  • Excessive Thirst
  • Inflammation Of The Tissue Lining The Sinuses
  • Large Purple Or Brown Skin Blotches

If experienced, these tend to have a Less Severe expression

  • Anxious Feelings
  • Diarrhea
  • Difficulty Sleeping
  • Dry Mouth
  • Excessive Sweating
  • Hearing Loss
  • Heart Throbbing Or Pounding
  • Indigestion
  • Sensation Of Spinning Or Whirling
  • Throat Irritation
  • Trouble Breathing
  • Upper Abdominal Pain
  • Urinary Tract Infection
  • Vomiting

RARE side effects


If experienced, these tend to have a Severe expression

  • A Blood Clot
  • A Broken Bone
  • A Condition With Symptoms That Resemble Lupus
  • A Goiter
  • A Heart Attack
  • A Herpes Simplex Infection
  • A High Alanine Transaminase Level
  • A High Aspartate Transaminase Level
  • A Respiratory Illness Called Loffler Syndrome
  • A Rupture In The Wall Of The Stomach Or Intestine
  • A Significant Type Of Allergic Reaction Called Anaphylaxis
  • A Skin Disorder With Blistering And Peeling Skin Called Stevens-Johnson Syndrome
  • A Skin Disorder With Blistering And Peeling Skin Called Toxic Epidermal Necrolysis
  • A Stomach Ulcer
  • A Stroke
  • A Systemic Inflammatory Response Called Sepsis Due To An Infection With Bacteria
  • A Type Of Allergic Reaction Called Angioedema
  • A Type Of Blood Disorder Where The Red Blood Cells Burst Called Hemolytic Anemia
  • A Type Of Blood Disorder With A Decrease In All Types Of Blood Cells Called Pancytopenia
  • A Type Of Kidney Inflammation Called Interstitial Nephritis
  • A Type Of Significant Allergic Skin Reaction Called DRESS Syndrome
  • A Type Of Skin Disorder Called Acute Generalized Exanthematous Pustulosis
  • A Type Of Stomach Irritation Called Gastritis
  • A Yellowing Of The Eyes Or Skin From Buildup Of Bilirubin Called Jaundice
  • Abnormal Heart Rhythm
  • Abnormal Liver Function Tests
  • Acute Inflammation Of The Pancreas
  • Aggressive Behavior
  • Agitation
  • An Ulcer From Too Much Stomach Acid
  • Anemia
  • Atrial Fibrillation
  • Bleeding Of The Stomach Or Intestines
  • Blockage Of The Stomach Or Intestine
  • Blood Coming From Anus
  • Bloody Urine
  • Bloody Vomit
  • Blurred Vision
  • Bronchospastic Lung Disease
  • Chest Tightness
  • Chronic Heart Failure
  • Coma
  • Confusion
  • Corneal Opacity, A Scarring Disorder That Results In Clouding Of The Cornea Of The Eye
  • Decreased Blood Platelets
  • Decreased Kidney Function
  • Decreased Lung Function
  • Depression
  • Diarrhea From An Infection With Clostridium Difficile Bacteria
  • Elevation Of Proteins In The Urine
  • Erythema Multiforme, A Type Of Allergic Skin Reaction
  • Excess Urination
  • Fainting
  • Fast Heartbeat
  • Fever
  • Fluid In The Lungs
  • Gallstones
  • Glomerulonephritis, A Condition That Affects The Kidneys
  • Hallucinations
  • Heart Failure
  • High Blood Pressure
  • High Blood Sugar
  • High Levels Of Potassium In The Blood
  • Hives
  • Increased Eosinophils In The Blood
  • Increased Sensitivity Of The Skin To The Sun
  • Inflammation Of The Bladder
  • Inflammation Of The Blood Vessels
  • Inflammation Of The Large Intestine
  • Inflammation Of The Lining Of The Stomach And Intestines
  • Inflammation Of The Liver Called Hepatitis
  • Inflammation Of The Skin Due To An Allergy
  • Itching
  • Joint Pain
  • Kidney Failure
  • Liver Failure
  • Low Amount Of Calcium In The Blood
  • Low Amount Of Potassium In The Blood
  • Low Amount Of Sodium In The Blood
  • Low Blood Counts Due To Bone Marrow Failure
  • Low Blood Pressure
  • Low Blood Sugar
  • Low Levels Of White Blood Cells
  • Meningitis Not Due To An Infection
  • Muscle Pain
  • Muscle Weakness
  • Nephrotic Syndrome, A Type Of Kidney Disorder
  • Non-Cancerous Growths In The Stomach Called Benign Fundic Gland Polyposis
  • Pancreatitis
  • Pneumonia
  • Pneumonia With High Amount Of Eosinophil White Blood Cells
  • Renal Papillary Necrosis
  • Renal Tubular Necrosis, A Kidney Disorder
  • Seizures
  • Skin Inflammation
  • Skin Rash With Sloughing
  • Stomach And Intestinal Infection Caused By The Fungus Candida
  • Stomach Or Intestinal Ulcer
  • Stomatitis, A Condition With Painful Swelling And Sores Inside The Mouth
  • Subacute Cutaneous Lupus Erythematosus
  • Sudden Blindness And Pain Upon Moving The Eye
  • Swollen Lymph Nodes
  • Systemic Lupus Erythematosus, An Autoimmune Disease
  • Trouble Breathing
  • Very Low Levels Of Granulocytes, A Type Of White Blood Cell
  • Wheezing

If experienced, these tend to have a Less Severe expression

  • A Common Cold
  • A Feeling Of General Discomfort Called Malaise
  • A Feeling Of Pins And Needles On Skin
  • A Painful, Red Or Swollen Tongue
  • A Problem With Menstrual Periods
  • A Skin Rash
  • A Type Of Stomach Irritation Called Gastritis
  • Abdominal Bloating
  • An Increased Need To Urinate Often
  • Anxious Feelings
  • Backache
  • Black Tarry Stools
  • Blistering Of The Skin
  • Burping
  • Changes In Appetite
  • Chest Pain
  • Chills
  • Decreased Appetite
  • Decreased Urine Production
  • Dehydration
  • Difficult Or Painful Urination
  • Difficulty Concentrating
  • Difficulty Sleeping
  • Difficulty Swallowing
  • Drowsiness
  • Dry Mouth
  • Enlarged Breasts
  • Erythema Nodosum, A Skin Condition With Red And Painful Nodules
  • Erythema Or Redness Of Skin Or Mucous Membrane
  • Excessive Sweating
  • Fast Heartbeat
  • Fever
  • Fluid Retention In The Legs, Feet, Arms Or Hands
  • Flu-Like Symptoms
  • Generalized Weakness
  • Hair Loss
  • Hallucinations
  • Heart Throbbing Or Pounding
  • Inadequate Vitamin B12
  • Increased Hunger
  • Increased Number Of Bowel Movements
  • Increased Sensitivity Of The Skin To The Sun
  • Ineffective Painful Straining Of Stool Or Urine
  • Inflammation Of The Esophagus
  • Inflammation Of The Large Intestine
  • Low Amount Of Magnesium In The Blood
  • Low Energy
  • Muscle Tremors
  • Muscle Weakness
  • Nervousness
  • Optic Disk Edema
  • Pain
  • Pink Eye
  • Puffy Face From Water Retention
  • Skin Disease Characterized By Swollen Itching Lesions
  • Slow Heartbeat
  • Stomatitis, A Condition With Painful Swelling And Sores Inside The Mouth
  • Taste Impairment
  • Temporary Redness Of Face And Neck
  • The Inability To Have An Erection
  • Visible Water Retention
  • Vomiting
  • Weight Gain
  • Weight Loss

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.