Ranolazine (Extended Release Granules)/Alcohol Interactions

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

Your medicine is designed to release your medicine throughout the day. Alcohol may speed up how quickly the medicine is released and may result in most or all of the medicine being released at one time.

What might happen:

The amount of medicine in your blood may increase rapidly and could cause side effects such as irregular heartbeat, which can be life-threatening.

What you should do about this interaction:

Avoid alcohol or liquid medicines which contain alcohol when using this medicine because it may cause the medication to be released too quickly and increase the risk of side effects. Let your doctor know right away if you notice an irregular heartbeat or have any dizziness or fainting episodes.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

  • 1.Aspruzyo Sprinkle (ranolazine) US prescribining information. Sun Pharmaceutical Industries, Inc. February, 2022.
  • 2.Drew BJ, Ackerman MJ, Funk M, Gibler WB, Kligfield P, Menon V, Philippides GJ, Roden DM, Zareba W. Prevention of torsade de pointes in hospital settings: a scientific statement from the American Heart Association and the American College of Cardiology Foundation. J Am Coll Cardiol 2010 Mar 2;55(9):934-47.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.