Zelboraf Side Effects by Likelihood and Severity

COMMON side effects


If experienced, these tend to have a Severe expression

  • A Type Of Bumpy Skin Rash Called A Maculopapular Rash
  • A Type Of Slow Growing Skin Cancer Called A Keratoacanthoma
  • Abnormal Liver Function Tests
  • Decreased Appetite
  • Diarrhea
  • Drug Or Chemical-Induced Sensitivity To Sunlight
  • Erythema Or Redness Of Skin Or Mucous Membrane
  • Fever
  • Nausea
  • Prolonged QT Interval On EKG
  • Squamous Cell Carcinoma
  • Vomiting

If experienced, these tend to have a Less Severe expression

  • A Roughened Red Patch Of Skin Called Actinic Keratosis
  • A Skin Rash
  • A Small, Soft Skin Growth Called Cutaneous Papilloma
  • Backache
  • Cough
  • Dry Skin
  • Fluid Retention In The Legs, Feet, Arms Or Hands
  • Generalized Weakness
  • Hair Loss
  • Itching
  • Joint Pain
  • Low Energy
  • Muscle Pain
  • Pain In The Arms Or Legs
  • Thickening Of The Outer Horny Layer Of The Skin

INFREQUENT side effects


If experienced, these tend to have a Severe expression

  • A Hypersensitivity Reaction To A Drug
  • A Painful Condition That Affects The Nerves In The Legs And Arms Called Peripheral Neuropathy
  • Arthritis
  • Basal Cell Carcinoma Of The Skin
  • Constipation
  • Erythema Nodosum, A Skin Condition With Red And Painful Nodules
  • Erythrodysesthesia Or Tingling, Pain, Redness, And Edema In The Hands And Feet
  • Inflammation Of The Blood Vessels

If experienced, these tend to have a Less Severe expression

  • Headache
  • High Blood Pressure
  • Inflammation Of A Hair Follicle
  • Pain In The Muscles Or Bones
  • Taste Impairment

RARE side effects


If experienced, these tend to have a Severe expression

  • A Blockage Of Blood Vessels In The Retina Of The Eye
  • A Deformity Of The Hand Called A Dupuytren's Contracture
  • A Significant Type Of Allergic Reaction Called Anaphylaxis
  • A Skin Disorder With Blistering And Peeling Skin Called Stevens-Johnson Syndrome
  • A Skin Disorder With Blistering And Peeling Skin Called Toxic Epidermal Necrolysis
  • A Type Of Kidney Inflammation Called Interstitial Nephritis
  • A Type Of Significant Allergic Skin Reaction Called DRESS Syndrome
  • Atrial Fibrillation
  • High Amount Of Bilirubin In The Blood
  • Increased Eosinophils In The Blood
  • Inflammation Of The Iris - The Colored Part Of The Eyeball
  • Inflammation Of The Liver Called Hepatitis
  • Inflammation Of The Uvea Of The Eye
  • Kidney Failure
  • Liver Failure
  • Low Blood Pressure
  • Low Levels Of A Type Of White Blood Cell Called Neutrophils
  • Pancreatitis
  • Progression Of Cancer With The RAS Mutation
  • Radiation Recall Syndrome
  • Radiation Sickness
  • Renal Tubular Necrosis, A Kidney Disorder
  • Squamous Cell Carcinoma Of Mouth

If experienced, these tend to have a Less Severe expression

  • A Condition With Nodules And Thickening Of Foot Tissue Called Plantar Fascial Fibromatosis
  • A Facial Nerve Disorder
  • An Inflammatory Condition Of Fat Under The Skin With Red Patches And Lumps Called Panniculitis
  • Blurred Vision
  • Visual Sensitivity To Light

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.