Exparel Vial Side Effects by Likelihood and Severity

COMMON side effects


If experienced, these tend to have a Less Severe expression

  • Constipation
  • Fever
  • Nausea
  • Vomiting

INFREQUENT side effects


If experienced, these tend to have a Severe expression

  • Anemia
  • Decreased Oxygen In The Tissues Or Blood
  • Low Blood Pressure
  • Ventricular Premature Beats

If experienced, these tend to have a Less Severe expression

  • A Sensation Of Feeling Warm
  • Backache
  • Confusion
  • Depression
  • Difficulty Sleeping
  • Drowsiness
  • Fluid Retention In The Legs, Feet, Arms Or Hands
  • Itching
  • Loss Of Skin Color
  • Low Energy And Weakness
  • Muscle Spasm
  • Numbness
  • Visible Water Retention

RARE side effects


If experienced, these tend to have a Severe expression

  • A Hypersensitivity Reaction To A Drug
  • A Significant Type Of Allergic Reaction Called Anaphylaxis
  • A Toxic Effect On The Central Nervous System, Which Consists Of The Brain And Spinal Cord
  • A Type Of Allergic Reaction Called Angioedema
  • A Type Of Slowed Heart Rhythm Disorder Called Heart Block
  • Abnormal Heart Rhythm
  • Abnormal Nervous System Function Affecting Alertness
  • Blood Clot In A Deep Vein Of The Extremities
  • Bundle Branch Block
  • Complete Stoppage Of The Heart
  • Damage To The Bone Cartilage In The Joint
  • Depression Of The Function Of The Heart
  • High Levels Of White Blood Cells
  • Hives
  • Lung Failure Causing Loss Of Breath
  • Methemoglobinemia, A Type Of Blood Disorder
  • Over Excitement
  • Paralysis
  • Seizures
  • Slow Heartbeat
  • Widening Of Blood Vessels

If experienced, these tend to have a Less Severe expression

  • A Feeling Of Pins And Needles On Skin
  • A Skin Rash
  • An Inability To Completely Empty The Bladder
  • Anxious Feelings
  • Blurred Vision
  • Chills
  • Dizziness
  • Erythema Or Redness Of Skin Or Mucous Membrane
  • Excessive Sweating
  • Fainting
  • Fast Heartbeat
  • Generalized Weakness
  • Hematoma, A Collection Of Blood Outside Of The Blood Vessels
  • Involuntary Leakage Of Urine
  • Muscle Tremors
  • Muscle Twitching
  • Muscle Weakness
  • Nervousness
  • Orthostatic Hypotension, A Form Of Low Blood Pressure
  • Pain In The Muscles Or Bones
  • Ringing In The Ears
  • Sneezing

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.