Ponatinib Tablet Side Effects by Likelihood and Severity

COMMON side effects


If experienced, these tend to have a Severe expression

  • A Blood Clot In An Artery
  • A Decreased Number Of Lymphocytes In The Blood
  • A High Alanine Transaminase Level
  • A High Aspartate Transaminase Level
  • An Infection
  • Anemia
  • Decreased Blood Platelets
  • Decreased Function Of Bone Marrow
  • Escape Of Fluid Into The Lungs
  • High Blood Pressure
  • Increased Alkaline Phosphatase
  • Low Levels Of A Type Of White Blood Cell Called Neutrophils
  • Low Levels Of White Blood Cells
  • Obstruction Of A Blood Vessel By A Blood Clot

If experienced, these tend to have a Less Severe expression

  • A Painful Condition That Affects The Nerves In The Legs And Arms Called Peripheral Neuropathy
  • A Skin Rash
  • Constipation
  • Cough
  • Decreased Appetite
  • Diarrhea
  • Dry Skin
  • Fever
  • Headache
  • High Blood Levels Of The Lipase Enzyme
  • Intense Abdominal Pain
  • Joint Pain
  • Low Energy
  • Muscle Pain
  • Nausea
  • Pain
  • Pain In The Arms Or Legs
  • Stomatitis, A Condition With Painful Swelling And Sores Inside The Mouth
  • Trouble Breathing
  • Vomiting

INFREQUENT side effects


If experienced, these tend to have a Severe expression

  • A Blockage Of Blood Vessels In The Retina Of The Eye
  • A Condition With Low Thyroid Hormone Levels
  • A Heart Attack
  • A Hemorrhage In The Brain
  • A Stroke
  • Atrial Fibrillation
  • Bleeding
  • Bleeding From The Retina
  • Bleeding Of The Stomach Or Intestines
  • Chronic Heart Failure
  • Pancreatitis
  • Peripheral Vascular Disease
  • Pneumonia
  • Supraventricular Arrhythmias, A Type Of Abnormal Heart Rhythm
  • Supraventricular Tachycardia

If experienced, these tend to have a Less Severe expression

  • A Feeling Of Pins And Needles On Skin
  • Backache
  • Blurred Vision
  • Bone Pain
  • Chills
  • Darkening Of The Skin
  • Difficulty Sleeping
  • Dizziness
  • Dry Eye
  • Eye Pain
  • Fluid Accumulation Around The Eye
  • Fluid Retention In The Legs, Feet, Arms Or Hands
  • High Blood Levels Of The Amylase Enzyme
  • Hyperesthesia, An Increased Nerve Sensitivity
  • Macular Edema
  • Muscle Spasm
  • Numbness
  • Water Retention
  • Weight Loss

RARE side effects


If experienced, these tend to have a Severe expression

  • A Blood Clot In A Retinal Vein
  • A Clot In The Small Veins That Carry Blood To Or From The Retina Of The Eye
  • A Clot Or Thrombosis Of The Mesenteric Artery Of The Intestines
  • A Gastrointestinal Tract Fistula
  • A Localized Weakening And Ballooning In An Artery Wall Called An Arterial Aneurysm
  • A Rupture In The Wall Of The Stomach Or Intestine
  • A Skin Disorder With Blistering And Peeling Skin Called Stevens-Johnson Syndrome
  • A Type Of Blood Clotting Disorder Called Disseminated Intravascular Coagulation
  • A Type Of Brain Disorder Called Posterior Reversible Encephalopathy Syndrome
  • A Type Of Slowed Heart Rhythm Disorder Called Heart Block
  • Abnormal Liver Function Tests
  • Acute Cerebral Infarction
  • An Ulcer Of The Cornea Of The Eye
  • Clouding Of The Lens Of The Eye Called Cataracts
  • Cranial Nerve Palsy
  • Damage To The Liver And Inflammation
  • Dehydration
  • Dissection Of Artery
  • Erythema Multiforme, A Type Of Allergic Skin Reaction
  • Extremely High Blood Pressure
  • Impaired Wound Healing
  • Inadequate Blood Flow In The Extremities
  • Inflammation Of The Iris - The Colored Part Of The Eyeball
  • Inflammation Of The Iris And Ciliary Body Of The Eye
  • Liver Failure
  • Overactive Thyroid Gland
  • Reactivation Of Hepatitis B Infection
  • Slow Heartbeat
  • Subdural Intracranial Hemorrhage
  • Thrombotic Thrombocytopenic Purpura, A Type Of Blood Disorder
  • Tumor Lysis Syndrome

If experienced, these tend to have a Less Severe expression

  • A Type Of Mole Called Acquired Melanocytic Nevus
  • An Inflammatory Condition Of Fat Under The Skin With Red Patches And Lumps Called Panniculitis
  • Cancer Of The Squamous Cells In The Skin
  • Glaucoma, An Increased Pressure In The Eye
  • Muscle Stiffness

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.