Mekinist Side Effects by Likelihood and Severity

COMMON side effects


If experienced, these tend to have a Severe expression

  • A Decreased Number Of Lymphocytes In The Blood
  • Anemia
  • Erythrodysesthesia Or Tingling, Pain, Redness, And Edema In The Hands And Feet
  • Low Amount Of Albumin Proteins In The Blood
  • Low Levels Of A Type Of White Blood Cell Called Neutrophils

If experienced, these tend to have a Less Severe expression

  • A Skin Rash
  • A Skin Rash Resembling Acne
  • Chills
  • Constipation
  • Decreased Appetite
  • Diarrhea
  • Erythema Or Redness Of Skin Or Mucous Membrane
  • Fever
  • Fluid Retention In The Legs, Feet, Arms Or Hands
  • High Blood Sugar
  • Lymphedema, Or Swelling Due To Blockage Of Lymph Nodes
  • Muscle Pain
  • Nausea
  • Night Sweats
  • Skin Inflammation
  • Trouble Breathing
  • Visible Water Retention
  • Vomiting

INFREQUENT side effects


If experienced, these tend to have a Severe expression

  • A Clot In The Lung
  • A Type Of Inflammation Of The Lung Called Interstitial Pneumonitis
  • A Type Of Slow Growing Skin Cancer Called A Keratoacanthoma
  • Bleeding
  • Blood Clot Formation In Vein
  • Blood Clot In A Deep Vein Of The Extremities
  • Cancer Of The Squamous Cells In The Skin
  • Cardiomyopathy, A Disease Of The Heart Muscle
  • Cellulitis
  • Decreased Blood Platelets
  • Heart Failure
  • High Blood Pressure
  • Inflammation Of A Hair Follicle
  • Low Amount Of Sodium In The Blood
  • Lung Tissue Problem

If experienced, these tend to have a Less Severe expression

  • Abnormal Liver Function Tests
  • Basal Cell Carcinoma Of The Skin
  • Blurred Vision
  • Dizziness
  • Dry Eye
  • Dry Mouth
  • Dry Skin
  • Fainting
  • Headache
  • Increased Sensitivity Of The Skin To The Sun
  • Inflammation And Infection Of Nail Cuticle
  • Intense Abdominal Pain
  • Itching
  • Joint Pain
  • Low Amount Of Phosphate In The Blood
  • Low Energy
  • Slow Heartbeat
  • Stomatitis, A Condition With Painful Swelling And Sores Inside The Mouth
  • Taste Impairment

RARE side effects


If experienced, these tend to have a Severe expression

  • A Blockage Of Blood Vessels In The Retina Of The Eye
  • A Change In Vision
  • A Condition With Muscle Tissue Breakdown Called Rhabdomyolysis
  • A Hemorrhage In The Brain
  • A Rupture In The Wall Of The Stomach Or Intestine
  • A Second Occurrence Of Melanoma
  • A Skin Disorder With Blistering And Peeling Skin Called Stevens-Johnson Syndrome
  • A Type Of Significant Allergic Skin Reaction Called DRESS Syndrome
  • Atrioventricular Block, A Type Of Slow Heart Rhythm Disorder
  • Bleeding Of The Stomach Or Intestines
  • Bundle Branch Block
  • Cancer Or Malignancy
  • Dehydration
  • Detachment Of Retinal Pigment Epithelium
  • Detachment Of The Retina Of The Eye
  • Inflammation Of The Iris - The Colored Part Of The Eyeball
  • Inflammation Of The Large Intestine
  • Inflammation Of The Uvea Of The Eye
  • Kidney Failure
  • Low Blood Pressure
  • Macular Edema
  • Sarcoidosis
  • Tear Of Retinal Pigment Epithelium
  • Tumor Lysis Syndrome

If experienced, these tend to have a Less Severe expression

  • A Decrease In Sharpness Of Vision Called Reduced Visual Acuity
  • A Painful Condition That Affects The Nerves In The Legs And Arms Called Peripheral Neuropathy
  • Abnormal Bleeding From The Uterus
  • Glaucoma, An Increased Pressure In The Eye
  • Nosebleed

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.