Who should not take Leflunomide?

The following conditions are contraindicated with this drug. Check with your physician if you have any of the following:

Conditions:

  • decreased kidney function
  • a painful condition that affects the nerves in the legs and arms called peripheral neuropathy
  • low levels of a type of white blood cell called neutrophils
  • decreased blood platelets
  • significantly decreased activity of the bone marrow
  • a type of blood disorder with a decrease in all types of blood cells called pancytopenia
  • a reduction in the body's resistance to infection
  • a bad infection
  • active tuberculosis
  • liver problems
  • abnormal liver function tests
  • hepatitis B
  • chronic hepatitis C
  • liver failure
  • pregnancy
  • acute inflammation of the liver due to hepatitis C virus
  • anemia
  • inactive tuberculosis
  • a patient who is producing milk and breastfeeding
  • lung tissue problem
  • a low amount of protein in the blood
  • high blood pressure

Allergies:

  • Pyrimidine Synthesis Inhibitor
  • Leflunomide

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.