Selected Hepatitis C Agents/Efavirenz; Etravirine;Nevirapine Interactions
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Medical warning:
Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
Efavirenz, etravirine, and nevirapine may speed up how quickly your body process your hepatitis medicine.
What might happen:
The amount of hepatitis medicine in your blood may decrease and it may not work as well.
What you should do about this interaction:
Let your healthcare professionals (e.g. doctor or pharmacist) know that you are taking these medicines together. Your doctor may want to perform some tests to see how much medicine is in your blood and how well it is working.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
- 1.Victrelis (boceprevir) US prescribing information. Schering Corporation January, 2017.
- 2.Sustiva (efavirenz) US prescribing information. Bristol-Myers Squibb Company November, 2023.
- 3.Incivek (telaprevir) US prescribing information. Vertex Pharmaceuticals Incorporated October, 2013.
- 4.Olysio (simeprevir) US prescribing information. Janssen Products, LP November, 2017.
- 5.Epclusa (sofosbuvir and velpatasvir) US prescribing information. Gilead Sciences, Inc. April, 2022.
- 6.Vosevi (sofosbuvir/velpatasvir/voxilaprevir) US prescribing information. Gilead Sciences, Inc. September, 2019.
- 7.Mavyret (glecaprevir and pibrentasvir) US prescribing information. AbbVie Inc. October, 2023.
- 8.Panel on Antiretroviral Guidelines for Adults and Adolescents. Guidelines for the use of antiretroviral agents in adults and adolescents Living with HIV. Department of Health and Human Services. Available at https://clinicalinfo.hiv.gov/en/guidelines/adult-and-adolescent-arv/whats- new-guidelines June 13, 2021.
- 9.Liverpool Drug Interactions Group. HIV Drug Interactions. Available at: https://hiv-druginteractions.org/.
- 10.Efavirenz-Emtricitabine-Tenefovir disoproxil Teva Sweden prescribing information. Teva Sweden AB October 20, 2017.
Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.