Indinavir/Efavirenz Interactions
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Medical warning:
Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
When indinavir is taken with efavirenz, your body may process indinavir more quickly.
What might happen:
When indinavir is taken with efavirenz, the beneficial effects of indinavir may decrease.
What you should do about this interaction:
Your healthcare professionals (e.g. doctor or pharmacist) may already be aware of this drug interaction and may be monitoring you for it. If your doctor prescribes these medicines together, it may be necessary to adjust your dose of indinavir. Do not start, stop, or change the dosage of any medicine before checking with them first.
- 1.Crixivan (indinavir sulfate) US prescribing information. Merck & Co., Inc. September, 2016.
- 2.Sustiva (efavirenz) US prescribing information. Bristol-Myers Squibb Company November, 2023.
- 3.Atripla (efavirenz/emtricitabine/tenofovir disoproxil fumarate) US prescribing information. Gilead Sciences, Inc. October, 2019.
Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.