Selected Live Viral Vaccines/Selected Immunoglobulins Interactions

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Very Serious. These medicines may interact and cause very harmful effects and are usually not taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

Immunoglobulins may prevent your immune system from properly responding to the vaccine.

What might happen:

The vaccine may not work and you may not develop immunity to the disease it is supposed to prevent.

What you should do about this interaction:

Let your healthcare professionals (e.g. doctor or pharmacist) know if you have any immunoglobulins in the previous year before receiving any vaccination.Let your healthcare professionals (e.g. doctor or pharmacist) know if you have had any vaccinations in the previous month before receiving any immunoglobulin. Your doctor may want to delay the immunoglobulin or repeat the vaccination after you have completed taking immunoglobulin.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

  • 1.CMV immunoglobulin-VF Australian prescribing information. CSL May 13, 2005.
  • 2.Zoster Immunoglobulin-VF Australian prescribing information. CSL Behring (Australia) Pty Ltd September 22, 2014.
  • 3.Normal immunoglobulin-VF Australian prescribing information. CSL August 10, 2006.
  • 4.RespiGam (respiratory syncytial virus) US prescribing information. MedImmune, Inc. May, 2000.
  • 5.Hepatitis B immunoglobulin-VF Australian prescribing information. CSL July 25, 2006.
  • 6.HyperHEP B (hepatitis B immune globulin (human)) US prescribing information. Talecris Biotherapeutics Inc. January, 2005.
  • 7.Human rabies immunoglobulin UK summary of product characteristics. Bio Products laboratory August 3, 2004.
  • 8.BatTet (human tetatus immune globulin) US prescribing information. Bayer Corporation March, 2004.
  • 9.Tetanus immunoglobulin Australian prescribing information. CSL July 25, 2006.
  • 10.Baytet (human tetanus immune globulin) Canadian prescribing information. Bayer 2004.
  • 11.Human tetanus immunoglobulin UK summary of product characteristics. Bio Products Laboratory August 3, 2004.
  • 12.BayGam (human immune globulin) US prescribing information. Bayer Corporation January, 2003.
  • 13.Bayhep B (human hepatits B immune globulin) Canadian prescribing information. Bayer 2004.
  • 14.Sandoglobulin NF (human normal immunoglobulin) UK summary of product characteristics. CSL Behring UK Limited Februray 13, 2006.
  • 15.Hyqvia (Immune Globulin 10% with Recombinant Hyaluronidase) Solution Prescribing Information. Baxter Healthcare Corporation September, 2014.
  • 16.Centers for Disease Control and Prevention. General Recommendations on Immunization. Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR. Available at: https://www.cdc.gov/vaccines/hcp/acip-recs/general-recs/index.html February 17, 2022;60(RR No.
  • 17):1-68.
  • 18.Babybig (botulinum neurotoxin a/b immune globulin) US prescribing information. California Department of Public Health June, 2021.
  • 19.Vigiv (vaccinia immune globulin intravenous, human) US prescribing information. Emergent BioSolutions Canada Inc. November, 2018.
  • 20.Anthrasil (anthrax immune globulin human liquid) US prescribing information. Emergent BioSolutions Canada Inc. May, 2018.

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.