Bortezomib/Venetoclax Interactions
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Medical warning:
Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
It is unknown what increases this risk.
What might happen:
More patients taking venetoclax with the combination of bortezomib and dexamethasone for multiple myeloma died than patients who were not taking bortezomib. Venetoclax is not approved for treatment of multiple myeloma.
What you should do about this interaction:
Tell your healthcare professionals (e.g. doctor or pharmacist) right away if you are taking these medicines together.Your healthcare professionals (e.g. doctor or pharmacist) may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
- 1.Venclexta (venetoclax) US prescribing information. AbbVie Inc. October, 2021.
- 2.FDA (US Food and Drug Administration). FDA Warns about the risks associated with the investigational use of Venclexta in Multiple Myeloma. available at: https://www.fda.gov/drugs/drug-safety-and-availability/fda-warns-about-ris ks-associated-investigational-use-venclexta-multiple-myeloma March 21, 2019.
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.