Selected Protease Inhibitors/Nevirapine Interactions

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

The cause of the interaction is not known.

What might happen:

Blood levels of your protease inhibitor may decrease, causing it to become less effective, or allowing your HIV to develop resistance to your medicine.

What you should do about this interaction:

Contact your healthcare professionals (e.g. doctor or pharmacist) about taking these two medicines together. They may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

  • 1.Marino RT. Personal communication. Boehringer Ingelheim Pharmaceuticals, Inc. February 7, 2001.
  • 2.Viramune (nevirapine) US prescribing information. Boehringer Ingelheim Pharmaceuticals, Inc. June, 2022.
  • 3.Agenerase (amprenavir) Oral Solution US prescribing information. GlaxoSmithKline May, 2005.
  • 4.Lexiva (fosamprenavir calcium) US prescribing information. GlaxoSmithKline March, 2019.
  • 5.Viracept (nelfinavir mesylate) US prescribing information. Agouron Pharmaceuticals, Inc. September, 2016.
  • 6.Invirase (saquinavir mesylate) US prescribing information. Roche Laboratories, Inc. March, 2019.
  • 7.Fortovase (saquinavir) US prescribing information. Roche Laboratories, Inc. December, 2004.
  • 8.Crixivan (indinavir sulfate) US prescribing information. Merck & Co., Inc. September, 2016.

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.