Zilretta Suspension,Extended Release Vial Side Effects by Likelihood and Severity

COMMON side effects


If experienced, these tend to have a Severe expression

  • An Infection

If experienced, these tend to have a Less Severe expression

  • Conditions Of Excess Stomach Acid Secretion
  • Difficulty Sleeping
  • High Blood Sugar
  • Steroid-Induced Hyperglycemia

INFREQUENT side effects


If experienced, these tend to have a Severe expression

  • A Hormone Disorder Where The Body Produces High Levels Of Cortisol Called Cushing's Syndrome
  • Bleeding Of The Stomach Or Intestines
  • Decreased Function Of The Adrenal Gland
  • Diabetes
  • Osteoporosis, A Condition Of Weak Bones

If experienced, these tend to have a Less Severe expression

  • A Feeling Of General Discomfort Called Malaise
  • An Increased Sodium Level In The Blood
  • Bruising
  • Cough
  • Inflammation Of The Tissue Lining The Sinuses
  • Irregular Periods
  • Reactions At The Site Of The Injection
  • Water Retention

RARE side effects


If experienced, these tend to have a Severe expression

  • A Broken Bone
  • A Disease With Shrinking And Weaker Muscles Called Myopathy
  • A Fat Embolism, A Type Of Clot Made Of Cholesterol Or Fat
  • A Rupture In The Wall Of The Stomach Or Intestine
  • A Significant Type Of Allergic Reaction Called Anaphylaxis
  • A Type Of Allergic Reaction Called Angioedema
  • Abnormal Heart Rhythm
  • Abnormal Liver Function Tests
  • An Enlarged Liver
  • An Infection Due To A Fungus
  • An Ulcer From Too Much Stomach Acid
  • Central Serous Chorioretinopathy
  • Chronic Heart Failure
  • Clouding Of The Lens Of The Eye Called Cataracts
  • Decreased Calcification Or Density Of Bone
  • Fluid In The Lungs
  • Glaucoma, An Increased Pressure In The Eye
  • High Blood Pressure
  • High Levels Of White Blood Cells
  • Hives
  • Impaired Wound Healing
  • Increased Pressure In The Eye
  • Inflammation Of The Blood Vessels
  • Inflammation Of The Liver Called Hepatitis
  • Insufficiency Of The Hypothalamus And Pituitary Gland
  • Low Amount Of Potassium In The Blood
  • Mental Problems From Taking The Drug
  • Obstruction Of A Blood Vessel By A Blood Clot
  • Pancreatitis
  • Pheochromocytoma
  • Pseudotumor Cerebri, A Condition With High Fluid Pressure In The Brain
  • Rupture Of A Tendon
  • Seizures
  • Slow Heartbeat
  • Thin Fragile Skin
  • Thrombophlebitis, An Inflamed Vein Due To A Blood Clot
  • Tumor Lysis Syndrome

If experienced, these tend to have a Less Severe expression

  • A Feeling Of Pins And Needles On Skin
  • A High Amount Of Calcium In Urine
  • A Skin Rash
  • Abdominal Bloating
  • Abnormal Fat Distribution
  • Acne
  • An Extreme Sense Of Wellbeing Called Euphoria
  • An Eye Infection
  • Arthritis
  • Blurred Vision
  • Bruising Under The Skin
  • Bulging Of The Eyes
  • Confusion
  • Decreased Pigmentation Of The Skin
  • Depression
  • Dry Skin
  • Erythema Or Redness Of Skin Or Mucous Membrane
  • Excessive Sweating
  • Fainting
  • Fast Heartbeat
  • Headache
  • Hiccups
  • Hirsutism, A Condition Of Hair Growth On Parts Of The Body Normally Without Hair
  • Increased Hunger
  • Infection At Injection Site
  • Inflammation Of The Esophagus
  • Inflammation Of The Skin Due To An Allergy
  • Itching
  • Itching Of The Genital Area
  • Joint Pain
  • Low Energy
  • Low Sperm Count
  • Memory Loss
  • Mood Changes
  • Muscle Pain
  • Muscle Spasm
  • Muscle Weakness
  • Nausea
  • Peripheral Sensory Nerve Disorder
  • Personality Disorders
  • Poisoning Caused By Anticholinergic Medication
  • Puffy Face From Water Retention
  • Sensation Of Spinning Or Whirling
  • Small Reddish-Purplish Pin-Point Sized Spots On Skin
  • Temporary Redness Of Face And Neck
  • Vaginal Bleeding After Menopause
  • Visible Water Retention
  • Weight Gain

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.