Cobicistat/Tenofovir disoproxil Interactions
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Medical warning:
Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
Cobicistat can increase the risk of damage on your kidneys.
What might happen:
Taking these medicines together may increase the risk of damage to your kidneys.
What you should do about this interaction:
Make sure your healthcare professionals (e.g. doctor or pharmacist) know that you are taking these medicines together. Let your doctor know if you experience a decrease in the amount of urine you make.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
- 1.Viread (tenofovir disoproxil fumarate) US prescribing information. Gilead Sciences, Inc. December, 2018.
- 2.Evotaz (atazanavir and cobicistat) Canada prescribing information. Bristol-Myers Squibb Company September, 2015.
- 3.Evotaz (atazanavir and cobicistat) UK summary of product characteristics. Bristol-Myers-Squibb Company March, 2016.
- 4.Evotaz (atazanavir and cobicistat) US prescribing information. Bristol-Myers-Squibb Company May, 2023.
- 5.Tybost (cobicistat) Canada prescribing information. Gilead Sciences Canada August, 2013.
- 6.Tybost (cobicistat) EMA summary of product characteristics. Gilead Sciences Limited May, 2014.
- 7.Tybost (cobicistat) US prescribing information. Gilead Sciences, Inc. September, 2021.
- 8.Prezcobix (darunavir-cobicistat) Canadian prescribing information. Janssen Inc. June 18, 2014.
- 9.Rezolsta (darunavir/cobicistat) UK summary of product characteristics. Janssen Pharmaceuticals Inc. March, 2016.
- 10.Prezcobix (darunavir and cobicistat) US prescribing information. Janssen Pharmaceuticals, Inc. March, 2023.
Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.