Halothane/Ketamine Interactions
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Medical warning:
Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
When these two medicines are given together, the beneficial effect of ketamine on your heart and blood system may be decreased.
What might happen:
You may experience a decrease in your blood pressure and slowing of your heartbeat.
What you should do about this interaction:
These two medicines are only used during surgical procedures or in a hospital. If you are to have either inpatient or outpatient surgery, or are to be admitted to the hospital, make sure that all the healthcare professionals are aware of all the different medicines that you are taking. This includes prescription medicines, herbal drugs, and nutraceuticals.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
- 1.Stanley TH. Blood-pressure and pulse-rate responses to ketamine during general anesthesia. Anesthesiology 1973 Dec;39(6):648-9.
- 2.Johnston RR, Miller RD, Way WL. The interaction of ketamine with d-tubocurarine, pancuronium, and succinylcholine in man. Anesth Analg 1974 Jul-Aug;53(4):496-501.
- 3.Bidwai AV, Stanley HT, Graves CL, Kawamura R, Sentker CR. The effects of ketamine on cardiovascular dynamics during halothane and enflurane anesthesia. Anesth Analg 1975 Sep-Oct;54(5):588-92.
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.