Acarbose; Miglitol/Amylase; Pancreatin Interactions

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Very Serious. These medicines may interact and cause very harmful effects and are usually not taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

When these two medicines are taken together, acarbose and miglitol may be broken down by digestive enzymes (e.g. amylase or pancreatin).

What might happen:

The beneficial effects of acarbose and miglitol may decrease and cause an increase in your blood sugar levels.

What you should do about this interaction:

Contact your doctor as soon as possible about taking these two medicines together. It may be necessary to change you to a different medicine. Your healthcare professionals (e.g. doctor or pharmacist) may already be aware of this drug interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

  • 1.Precose (arcarbose) US prescribing information. Bayer Pharmaceuticals Corporation March, 2015.
  • 2.Glyset (miglitol) US prescribing information. Pharmacia & Upjohn Company September, 2012.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.