Larotrectinib Capsule Side Effects by Likelihood and Severity

COMMON side effects


If experienced, these tend to have a Severe expression

  • A Decreased Number Of Lymphocytes In The Blood
  • A High Alanine Transaminase Level
  • A High Aspartate Transaminase Level
  • Abnormal Liver Function Tests
  • Anemia
  • Increased Alkaline Phosphatase
  • Low Amount Of Albumin Proteins In The Blood
  • Low Amount Of Calcium In The Blood
  • Low Levels Of A Type Of White Blood Cell Called Neutrophils
  • Low Levels Of White Blood Cells

If experienced, these tend to have a Less Severe expression

  • A Sleep Disorder
  • Constipation
  • Cough
  • Diarrhea
  • Dizziness
  • Fever
  • Low Energy
  • Mood Changes
  • Nausea
  • Vomiting

INFREQUENT side effects


If experienced, these tend to have a Severe expression

  • A Broken Bone
  • A Systemic Inflammatory Response Called Sepsis Due To An Infection With Bacteria
  • A Yellowing Of The Eyes Or Skin From Buildup Of Bilirubin Called Jaundice
  • Abnormal Manner Of Walking
  • Cellulitis
  • Delirium
  • High Blood Pressure
  • Low Amount Of Sodium In The Blood

If experienced, these tend to have a Less Severe expression

  • A Change In The Ability To Pay Attention
  • A Feeling Of Pins And Needles On Skin
  • A Type Of Speech Disorder Called Dysarthria
  • Agitation
  • Anxious Feelings
  • Backache
  • Confusion
  • Decreased Appetite
  • Dehydration
  • Depression
  • Drowsiness
  • Fainting
  • Generalized Weakness
  • Hallucinations
  • High Blood Levels Of The Amylase Enzyme
  • High Blood Levels Of The Lipase Enzyme
  • Intense Abdominal Pain
  • Irritability
  • Joint Pain
  • Memory Loss
  • Muscle Pain
  • Muscle Tremors
  • Muscle Weakness
  • Pain
  • Peripheral Sensory Nerve Disorder
  • Stuffy Nose
  • Trouble Breathing
  • Weight Gain

RARE side effects


If experienced, these tend to have a Severe expression

  • A Hole In The Intestine
  • A Type Of Brain Function Problem Called Encephalopathy
  • Accidental Falls
  • Acute Myeloid Leukemia, A Type Of Blood Cancer
  • Blockage Of The Stomach Or Intestine
  • Damage To The Liver And Inflammation
  • Enterocutaneous Fistula
  • Escape Of Fluid Into The Lungs
  • Fluid Accumulation In The Brain
  • Fluid In The Covering Of The Heart Or Pericardium
  • High Amount Of Bilirubin In The Blood

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.