Hormonal Contraceptives/Asunaprevir Interactions

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

When these two medicines are taken together, your body may process your birth control faster.

What might happen:

The effects of your birth control pills may decrease and cause breakthrough bleeding, spotting, or pregnancy. The effects of the interaction may last for several weeks after you stop taking asunaprevir.

What you should do about this interaction:

Make sure your healthcare professionals (e.g. doctor or pharmacist) know that you are taking these medicines together. Your doctor may want to change your medicines or increase the dose of your birth control pills.Emergency contraceptives may be less effective also. You may need a larger dose than normal. Discuss the dose and the need to confirm that you do not become pregnant with a pregnancy test with your healthcare professional.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

  • 1.Sunvepra (asunaprevir) Australia Prescribing Information. Bristol-Myers Squibb Australia Pty Ltd April 5, 2019.
  • 2.Medicines and Healthcare products Regulatory Agency. Levonorgestrel-containing emergency hormonal contraception: advice on interactions with hepatic enzyme inducers and contraceptive efficacy. available at: https://www.gov.uk/drug-safety-update/levonorgestrel-containing-emergency- hormonal-contraception-advice-on-interactions-with-hepatic-enzyme-inducers -and-contraceptive-efficacy September 15, 2016..
  • 3.Sunvepra (asunaprevir) Canadian prescribing information. Bristol-Myers Squibb Canada January 26, 2017.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.