Ethinyl Estradiol (greater than 30 mcg)/Fostemsavir Interactions

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Very Serious. These medicines may interact and cause very harmful effects and are usually not taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

It is unknown how this interaction occurs.

What might happen:

The combination of these two medicines may increase the amount of ethinyl estradiol in your blood and cause more side effects than usual, including blood clots.

What you should do about this interaction:

Make sure your healthcare professionals (e.g. doctor or pharmacist) know that you are taking these medicines together and if you smoke, have a history of blood clots, problems with your blood, or heart disease; or if you have been confined to a bed or wheelchair. These conditions may also increase your risk of a blood clot.Contact your doctor right away if you develop pain and/or swelling of an arm or leg with warmth over the area, discoloration of an arm or leg, unexplained shortness of breath, chest pain or discomfort that worsens on deep breathing, unexplained rapid pulse, excessive sweating, and/or numbness on one side of your body.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

  • 1.Rukobia (fostemsavir) US prescribing information. ViiV Healthcare July, 2020..

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.