COVID-19 Vaccines/COVID-19 Monoclonal Antibodies Interactions

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

COVID-19 antibody may prevent your immune system from properly responding to the COVID-19 vaccine.

What might happen:

There is a chance that the vaccine may not prevent COVID-19 infection. There have been no specific studies to address this possible risk.

What you should do about this interaction:

Let your healthcare professionals (e.g. doctor or pharmacist) know if you have received any COVID-19 vaccine in the past 2 weeks. Your healthcare provider may want to delay administration of COVID-19 antibody as a precaution.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

  • 1.Centers for Disease Control and Prevention (CDC). Interim Clinical Considerations for Use of COVID-19 Vaccines Currently Approved or Authorized in the United States. Accessed at: https://www.cdc.gov/vaccines/covid-19/clinical-considerations/covid-19-vac cines-us.html Last updated: September 15, 2023.
  • 2.Evushield (tixagemivab co-packaged with cilgavimab) Fact Sheet for Healthcare Providers (EUA). AstraZeneca December 2021.
  • 3.Pemgarda (pemivibart) injection US prescribing information. Invivyd, Inc 03/2024.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.