What should I Know Regarding Pregnancy, Nursing and Administering Methadone 10 Mg/Ml In Sodium Chloride,Iso-Osmotic Intravenous Syringe Opioid Analgesics- ER (With All Antitussive Opiates) to Children or the Elderly?

If you are PREGNANT

  • Requires a Risk/Benefit Assessment:

If you are NURSING

  • Precaution: BREASTFEEDING ACCEPTABLE DURING TREATMENT; MONITOR INFANT FOR RESP DEPRESSION

If you are an adult over 60

  • Management or Monitoring Precaution: Pulmonary-DO NOT use in opioid intolerance. Increased risk of fatal respiratory depression due to altered pharmacokinetics. Monitor closely at initiation and dose titration and when giving with other drugs that cause respiratory depression. Consider naloxone Rx. Renal-Start with low dose for renal impairment. Neuro/Psych-Risk for confusion, delirium and falls. Avoid treatment with 3 or more CNS active agents. Cardiovascular-QT prolongation risk; syncope risk.

Giving Methadone 10 Mg/Ml In Sodium Chloride,Iso-Osmotic Intravenous Syringe Opioid Analgesics- ER (With All Antitussive Opiates) to a child under 12

  • Severe Precaution: Potential increased sensitivity to effects, adverse CNS effects and respiratory depression. Safety, effectiveness, and pharmacokinetics not established in pediatric patients. With any opioid, access to naloxone for emergency reversal can mitigate risk from accidental ingestion/overdose.
  • Management or Monitoring Precaution: Safety, effectiveness, and pharmacokinetics not established in age < 18 years. With any opioid, access to naloxone for emergency reversal can mitigate risk from accidental ingestion/overdose.
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.