Depakote ER Side Effects by Likelihood and Severity

COMMON side effects

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If experienced, these tend to have a Severe expression

• An Accidental Injury
• Decreased Blood Platelets
• Fluid Retention In The Legs, Feet, Arms Or Hands
• Nystagmus, A Condition With Involuntary Eye Movements
• Trouble Breathing

If experienced, these tend to have a Less Severe expression

• A Stuffy And Runny Nose
• An Infection
• Blurred Vision
• Bronchitis
• Bruising Under The Skin
• Constipation
• Decreased Appetite
• Depression
• Diarrhea
• Difficulty Sleeping
• Dizziness
• Double Vision
• Drowsiness
• Fever
• Flu-Like Symptoms
• Generalized Weakness
• Hair Loss
• Headache
• Increased Hunger
• Indigestion
• Intense Abdominal Pain
• Irregular Periods
• Loss Of Muscle Coordination
• Memory Loss
• Muscle Tremors
• Nausea
• Ringing In The Ears
• Throat Irritation
• Vomiting
• Weight Gain
• Weight Loss

INFREQUENT side effects

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If experienced, these tend to have a Severe expression

• Mental Status Changes
• Mood Changes

If experienced, these tend to have a Less Severe expression

• Abnormal Manner Of Walking
• Backache
• Irritability
• Nervousness
• Reactions At The Site Of The Injection
• Taste Impairment
• Widening Of Blood Vessels

RARE side effects

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If experienced, these tend to have a Severe expression

• A Brain Condition Called Cerebral Pseudoatrophy
• A Broken Bone
• A Decrease In Platelet Clotting
• A Disorder With Excess Antidiuretic Hormone Called Syndrome Of Inappropriate Antidiuretic Hormone
• A Paradoxical Convulsion
• A Significant Type Of Allergic Reaction Called Anaphylaxis
• A Skin Disorder With Blistering And Peeling Skin Called Stevens-Johnson Syndrome
• A Skin Disorder With Blistering And Peeling Skin Called Toxic Epidermal Necrolysis
• A Type Of Blood Disorder With A Decrease In All Types Of Blood Cells Called Pancytopenia
• A Type Of Brain Function Problem Called Encephalopathy
• A Type Of Kidney Inflammation Called Interstitial Nephritis
• A Type Of Movement Disorder Called Parkinsonism
• A Type Of Significant Allergic Skin Reaction Called DRESS Syndrome
• A Yellowing Of The Eyes Or Skin From Buildup Of Bilirubin Called Jaundice
• Abnormal Liver Function Tests
• Abnormally Large Red Blood Cells Called Macrocytosis
• Accidental Falls
• Acute Inflammation Of The Pancreas
• Acute Liver Failure
• An Abnormal Sperm Size Or Shape
• Anemia
• Behavioral Problems
• Bloody Vomit
• Carnitine Deficiency
• Erythema Multiforme, A Type Of Allergic Skin Reaction
• Hearing Loss
• Hereditary Liver Metabolism Disorder
• High Amount Of Ammonium In The Blood
• High Blood Pressure
• High Levels Of Androgen Hormones
• Increased Eosinophils In The Blood
• Increased Lymphocyte Cells In The Blood
• Increased Sensitivity Of The Skin To The Sun
• Inflammation Of Blood Vessels In The Skin
• Inflammation Of The Bladder
• Inflammation Of The Liver Called Hepatitis
• Inflammation Of The Middle Tissue Heart Muscle
• Kidney Inflammation
• Low Blood Counts Due To Bone Marrow Failure
• Low Body Temperature
• Low Levels Of White Blood Cells
• Male Infertility
• Osteoporosis, A Condition Of Weak Bones
• Polycystic Ovarian Syndrome, A Disease With Cysts In The Ovaries
• Puffy Face From Water Retention
• Slow Heartbeat
• Suicidal Thoughts
• Swollen Lymph Nodes
• Tardive Dyskinesia, A Disorder Characterized By Involuntary Movements Of The Face, Mouth And Tongue
• Very Low Levels Of Granulocytes, A Type Of White Blood Cell

If experienced, these tend to have a Less Severe expression

• A Change In The Ability To Pay Attention
• A Change In Vision
• A Feeling Of General Discomfort Called Malaise
• A Nail Disorder
• A Problem With Menstrual Periods
• A Skin Rash
• A Type Of Bumpy Skin Rash Called A Maculopapular Rash
• Abnormal Dreams
• Abnormal Hair Texture
• Absence Of Menstrual Periods
• Absence Of Sperm In Semen
• Acquired Pelger-Huet Anomaly
• Aggressive Behavior
• Agitation
• An Abnormal Increase In Muscle Tone
• An Increased Need To Urinate Often
• Anxious Feelings
• Bleeding Not Related To Menstrual Period
• Bone Pain
• Breastmilk Production Not Associated With Childbirth Or Nursing
• Cessation Of Menstruation
• Chest Pain
• Cough
• Decreased Calcification Or Density Of Bone
• Decreased Sperm Motility
• Difficult Or Painful Urination
• Diminished Movement
• Dry Mouth
• Dry Skin
• Enlarged Breasts
• Exaggerated Deep Reflexes
• Fast Heartbeat
• Feelings Of Hostility
• Gas
• Hair Discoloration
• Heart Throbbing Or Pounding
• Hirsutism, A Condition Of Hair Growth On Parts Of The Body Normally Without Hair
• Indifferent Behavior
• Inflammation Of The Parotid Gland
• Inflammation Of The Tissue Lining The Sinuses
• Involuntary Leakage Of Urine
• Leg Cramps
• Low Sperm Count
• Muscle Weakness
• Nosebleed
• Over Excitement
• Pain With Menstruation
• Panic Disorder
• Personality Disorders
• Pink Eye
• Seborrhea
• Sensation Of Spinning Or Whirling
• Small Reddish-Purplish Pin-Point Sized Spots On Skin
• Stomatitis, A Condition With Painful Swelling And Sores Inside The Mouth
• Toxic Amblyopia, A Loss Of Vision
• Urinary Tract Infection