Ombitasvir-Paritaprevir/Lopinavir-Ritonavir Interactions

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

Lopinavir-ritonavir may slow down how quickly your liver processes your hepatitis C medicine.

What might happen:

The amount of your hepatitis C medicine in your blood may increase and cause increased side effects.

What you should do about this interaction:

Let your healthcare professionals (e.g. doctor or pharmacist) know that you are taking these medicines together. Let your doctor know if you have any side effects from your medicine. Your doctor may want to change your medicine.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

  • 1.Technivie (ombitasvir-paritaprevir-ritonavir) US prescribing information. Abbvie Inc. December, 2019.
  • 2.Viekira Pak (ombitasvir, paritaprevir, and ritonavir; dasabuvir) US prescribing information. AbbVie Inc. December, 2019.
  • 3.FDA. CDER Application number: 2066190 Viekira Pak (ombitasvir, paritaprevir, ritonavir, dasabuvir) Clinical Pharmacology and Biopharmaceutics Review(s). URL: http://www.accessdata.fda.gov/drugsatfda_docs/nda/2014/206619Orig1s000Clin PharmR.pdf December 19, 2014.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.