What should I Know Regarding Pregnancy, Nursing and Administering Ziprasidone Hcl to Children or the Elderly?

If you are PREGNANT

  • Requires a Risk/Benefit Assessment:

If you are NURSING

  • Absolute Contraindication: LIMITED DATA SUGGEST EXCRETION; LACTMED RECOMMENDS ALTERNATE TREATMENT

If you are an adult over 60

  • Management or Monitoring Precaution: Neuro/Psych-Higher risk of tardive dyskinesia. Anticholinergic effects cause sedation, worsen cognitive impairment and increase fall risk. Increased risk of death in senile dementia. Cardiovascular-Risk of orthostatic hypotension, dizziness, QT prolongation. Avoid use if significant cardiovascular condition. Monitor for hyperglycemia, lipid changes, weight gain. Gastrointestinal-May cause or worsen pre-existing constipation. Urogenital-Avoid in patients with urinary retention.

Giving Ziprasidone Hcl to a child under 12

  • Severe Precaution: Adverse reactions include weight gain, glucose and lipid abnormalities, QT prolongation. Safety and efficacy in pediatrics not established.
  • Management or Monitoring Precaution: Risk of sedation, dystonia, extrapyramidal reactions, QT prolongation, hyperprolactinemia, lipid, glucose abnormalities. Monitor weight. No safety and efficacy per manufacturer.
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