Vadadustat/Erythropoietin Stimulating Agents Interactions
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Medical warning:
Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
Vadadustat and erythropoietin stimulating agents both increase the risk of blood clots.
What might happen:
You may be at a higher risk for heart attack, stroke, or blood clots in the blood vessels in your legs or lungs when taking these two medicines together.
What you should do about this interaction:
Let your healthcare professionals (e.g. doctor or pharmacist) know that you are taking these medicines together.Seek medical care immediately if you experience chest pain; shortness of breath; pain in your arms, neck, jaw or back; swelling, pain, or tenderness in your legs; sudden numbness of weakness, especially on one side of the body; headache or confusion; or problems with vision, speech, or balance.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
- 1.Vafseo (vadadustat) Australian prescribing information. Akebia Therapeutics, Inc. October, 2023.
- 2.Vafseo (vadadustat) UK Summary of Product Characteristics. Akebia Europe Limited May, 2023.
- 3.Aranesp (darbepoetin alfa) US prescribing information. Amgen Inc April 13, 2017.
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.