Sodium Oxybate/Sedative Hypnotics; Alcohol Interactions
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Medical warning:
Very Serious. These medicines may interact and cause very harmful effects and are usually not taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
Sodium oxybate, sedating medicines and alcohol affect your central nervous system.
What might happen:
You may experience an increase in side effects such as excessive sedation, confusion, agitation, or loss of coordination.
What you should do about this interaction:
Contact your healthcare professionals (e.g. doctor or pharmacist) right away about taking these medicines together. If you are sleeping too long at night or experience confusion, agitation, or loss of coordination, contact your doctor.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
- 1.Xyrem (sodium oxybate) US prescribing information. Jazz Pharmaceuticals, Inc. April, 2023.
- 2.Lumryz (sodium oxybate extended-release oral suspension) US prescribing information. Avadel CNS Pharmaceuticals, LLC May, 2023.
- 3.USFood and Drug Administration. FDA Drug Safety Communication: Warning against use of Xyrem (sodium oxybate) with alcohol or drugs causing respiratory depression. available at: http://www.fda.gov/Drugs/DrugSafety/ucm332029.htm December 17, 2012.
- 4.USFood and Drug Administration (FDA). Docetaxel: Drug Safety Communication - May Cause Symptoms of Alcohol Intoxication. available at: https://www.fda.gov/drugs/drug-safety-and-availability/fda-drug-safety-com munication-fda-warns-cancer-drug-docetaxel-may-cause-symptoms-alcohol June 20, 2014.
Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.