Selected Anticoagulants (Vit K antagonists)/Tibolone Interactions
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Medical warning:
Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
Tibolone can decrease your body's ability to make clots. When these two medicines are taken together, the effects of your anticoagulant (blood-thinner) may be increased.
What might happen:
You may experience an increased chance for bleeding including bleeding from your gums, nosebleeds, unusual bruising, or dark stools.
What you should do about this interaction:
Contact your healthcare professionals (e.g. doctor or pharmacist) as soon as possible about taking these two medicines together. They may already be aware of this interaction and may be monitoring you for it. If your doctor prescribes these medicines together, you may need to check your bleeding times more often. Do not start, stop, or change the dosage of any medicine before checking with them first.
- 1.Livial (tibolone) Australian prescribing information. Merck Sharp & Dohme (Australia) Pty Limited May 17, 2016.
- 2.McLintock LA, Dykes A, Tait RC, Walker ID. Interaction between hormone replacement therapy preparations and oral anticoagulant therapy. BJOG 2003 Aug;110(8):777-9.
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.