Coumarin Anticoagulants/Glucagon, Dasiglucagon Interactions
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Medical warning:
Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
The cause of this interaction is not known.
What might happen:
You may experience an increased chance for bleeding including bleeding from your gums, nosebleeds, unusual bruising, or dark stools.
What you should do about this interaction:
You should watch for any unusual bleeding or bruising. If your doctor prescribes these medicines together and you need to receive glucagon injections regularly, the doctor may need to check your bleeding times more often. You may need an adjustment in the dose of your blood thinner.Make sure that your doctor knows all of the medicines that you are taking.Your healthcare professionals (e.g. doctor or pharmacist) may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
- 1.Koch-Weser J. Potentiation by glucagon of the hypoprothrombinemic action of warfarin. Ann Intern Med 1970 Mar;72(3):331-5.
- 2.Weiner M, Moses D. The effect of glucagon and insulin on the prothrombin response to coumarin anticoagulants. Proc Soc Exp Biol Med 1968 Mar; 127(3):761-3.
- 3.Zegalogue (Dasiglucagon) US Prescribing Information. Zealand Pharma A/S March 2021.
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.