Non-Live Vaccines/Satralizumab Interactions

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

Satralizumab decreases your immune system's response to vaccination.

What might happen:

Vaccinations may not work as well if administered during satralizumab treatment.

What you should do about this interaction:

Make sure your healthcare professionals (e.g. doctor or pharmacist) know that you are taking satralizumab. Your doctor may want to perform a blood test a few weeks after your vaccination to determine if the vaccine worked.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

  • 1.Enspryng (satralizumab-mwge) US Prescribing Information. Genentech, Inc. August 2020.
  • 2.Kroger A Bahta L Long S Sanchez P. General Best Practice Guideline for Immunization. Best Practices Guidance of the Advisory Committee on Immunzation Practices (ACIP). MMWR. Available at: recs.pdf February 10, 2023;1-197.

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.