Cholera Vaccine Live/Selected Antibiotics Interactions

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

When these two medicines are taken together, the vaccine may not work as well.

What might happen:

The vaccine may be ineffective.

What you should do about this interaction:

Before receiving a cholera vaccination, let your doctor know if you are taking an antibiotic or have taken an antibiotic in the past two weeks, or if are scheduled to start taking medicine to prevent malaria.Your healthcare professionals (e.g. doctor or pharmacist) may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

  • 1.Vaxchora (Cholera Vaccine, Live, Oral) US prescribing information. PaxVax Inc. June, 2016.
  • 2.Centers for Disease Control and Prevention (CDC). Recommendations for the Use of Antibiotics for the Treatment of Cholera. accessed at: Last updated January 20, 2015.
  • 3.Australian Government Department of Health Office of the Gene Technology Regulator. Risk Assessment and Risk Management Plan for DIR126, Clinical trial of a genetically modified vaccine against Cholera (applicant: PaxVax Australia Pty Ltd). April, 2004.

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.