Slt Long-Acting Aripiprazole/Strong CYP3A4 Inhibitors; Atazanavir; Interactions

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.

Medical warning:

Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.

How the interaction occurs:

Some medicines may slow down (inhibit) how quickly your liver processes aripiprazole.

What might happen:

The amount of aripiprazole in your blood may increase and cause more side effects than normal.

What you should do about this interaction:

Let your healthcare professionals (e.g. doctor or pharmacist) know that you are taking these medicines together. Your doctor may want to change your dose of aripiprazole while you are taking your other medicine, or change your medicines. Let your doctor know if you notice an increase in side effects while taking these medicines together, especially increased restlessness, anxiety, muscle stiffness, confusion, sweating, involuntary movements, dizziness or fainting when getting up from a seated or lying position, or trouble with sleep (either feeling too sleepy or having trouble getting enough/restful sleep).Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

  • 1.Abilify Asimtufii (aripiprazole extended-release injectable) US prescribing information. Otsuka Pharmaceutical Co., Ltd. April, 2023.
  • 2.Aristada (aripiprazole lauroxil) extended-release injectable US prescribing information. Alkermes Inc. November, 2018.
  • 3.This information is based on an extract from the Certara Drug Interaction Database (DIDB) Platform, Copyright Certara 1999-2023..

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.