Cyclophosphamide Side Effects by Likelihood and Severity

COMMON side effects


If experienced, these tend to have a Severe expression

  • A Reduction In The Body's Resistance To Infection
  • An Infection
  • Low Levels Of A Type Of White Blood Cell Called Neutrophils
  • Low Levels Of White Blood Cells

If experienced, these tend to have a Less Severe expression

  • Darkening Of The Skin
  • Decreased Appetite
  • Diarrhea
  • Discoloration Of Nail
  • Fever
  • Hair Loss
  • Irregular Periods
  • Nausea
  • Vomiting

INFREQUENT side effects


If experienced, these tend to have a Severe expression

  • A Disorder With Excess Antidiuretic Hormone Called Syndrome Of Inappropriate Antidiuretic Hormone
  • A Yellowing Of The Eyes Or Skin From Buildup Of Bilirubin Called Jaundice
  • Anemia
  • Damage To The Kidneys
  • Decreased Blood Platelets
  • Inflammation Of The Bladder With Hemorrhage
  • Tumor Lysis Syndrome

If experienced, these tend to have a Less Severe expression

  • Absence Of Menstrual Periods
  • Absence Of Sperm In Semen
  • Excessive Sweating
  • Headache
  • Intense Abdominal Pain
  • Low Sperm Count
  • Temporary Redness Of Face And Neck

RARE side effects


If experienced, these tend to have a Severe expression

  • A Clot In The Lung
  • A Condition Where There Is Formation Of Fibrous Tissue In The Lung Called Pulmonary Fibrosis
  • A Condition With Muscle Tissue Breakdown Called Rhabdomyolysis
  • A Heart Attack
  • A Significant Type Of Allergic Reaction Called Anaphylaxis
  • A Skin Disorder With Blistering And Peeling Skin Called Stevens-Johnson Syndrome
  • A Skin Rash
  • A Type Of Allergic Reaction Called Angioedema
  • A Type Of Blood Clotting Disorder Called Disseminated Intravascular Coagulation
  • A Type Of Brain Disorder Called Posterior Reversible Encephalopathy Syndrome
  • A Type Of Brain Function Problem Called Encephalopathy
  • A Type Of Inflammation Of The Lung Called Interstitial Pneumonitis
  • Abnormal Liver Function Tests
  • Acute Inflammation Of The Covering Of The Heart
  • Acute Inflammation Of The Pancreas
  • An Abnormal Bleed In The Heart Muscle
  • An Enlarged Liver
  • Atrial Fibrillation
  • Atrial Flutter
  • Bleeding Of The Stomach Or Intestines
  • Blockage Of Normal Bile Flow
  • Blood Clot Formation In Vein
  • Bronchospastic Lung Disease
  • Cancer Of The Bladder
  • Erythema Multiforme, A Type Of Allergic Skin Reaction
  • Erythrodysesthesia Or Tingling, Pain, Redness, And Edema In The Hands And Feet
  • Fluid In The Covering Of The Heart Or Pericardium
  • Hearing Loss
  • Heart Failure
  • Hemolytic Uremic Syndrome, A Condition That Affects The Kidney And The Blood
  • Hepatic Veno-Occlusive Disease, A Type Of Liver Disease
  • High Blood Pressure
  • High Blood Sugar
  • Hives
  • Impaired Wound Healing
  • Inadequate Blood Flow In The Extremities
  • Infertility
  • Inflammation Of The Bladder
  • Inflammation Of The Large Intestine
  • Inflammation Of The Lining Of The Stomach And Intestines
  • Inflammation Of The Liver Called Hepatitis
  • Inflammation Of The Middle Tissue Heart Muscle
  • Inflammation Of The Skin Due To An Allergy
  • Itching
  • Kidney Failure
  • Liver Failure
  • Low Amount Of Sodium In The Blood
  • Low Blood Pressure
  • Lung Tissue Problem
  • Myelodysplastic Syndrome, A Bone Marrow Disorder
  • Pericardial Tamponade, A Disorder Of The Heart
  • Pulmonary Hypertension
  • Pulmonary Veno-Occlusive Disease
  • Radiation Recall Syndrome
  • Reactions At The Site Of The Injection
  • Scleroderma, Hardening And Tightening Of The Skin And Connective Tissues
  • Seizures
  • Stomatitis, A Condition With Painful Swelling And Sores Inside The Mouth
  • Supraventricular Arrhythmias, A Type Of Abnormal Heart Rhythm
  • Thyroid Cancer
  • Trouble Breathing
  • Ventricular Arrhythmias, A Type Of Abnormal Heart Rhythm

If experienced, these tend to have a Less Severe expression

  • A Distorted Sense Of Smell Called Parosmia
  • Confusion
  • Constipation
  • Excessive Watery Eyes
  • Inflammation Of The Parotid Gland
  • Muscle Spasm
  • Pain In The Oropharynx
  • Pink Eye
  • Ringing In The Ears
  • Taste Impairment
  • Water Retention

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.