Carbidopa-Levodopa-Entacapone Side Effects by Likelihood and Severity

COMMON side effects


If experienced, these tend to have a Severe expression

  • A Feeling Of Restlessness With Inability To Sit Still
  • A Type Of Abnormal Movement Disorder Called Dyskinesia
  • Diminished Movement
  • Hallucinations
  • Hyperactive Behavior
  • Orthostatic Hypotension, A Form Of Low Blood Pressure

If experienced, these tend to have a Less Severe expression

  • A Type Of Abnormal Movement Disorder Called Dyskinesia
  • Abnormal Color Of Urine
  • Anxious Feelings
  • Constipation
  • Diarrhea
  • Difficulty Sleeping
  • Dizziness
  • Headache
  • Intense Abdominal Pain
  • Loss Of Muscle Coordination
  • Low Energy
  • Mental Status Changes
  • Nausea
  • Vomiting

INFREQUENT side effects


If experienced, these tend to have a Severe expression

  • A Bacterial Infection
  • Fainting
  • Involuntary Eyelid Twitching
  • Orthostatic Hypotension, A Form Of Low Blood Pressure

If experienced, these tend to have a Less Severe expression

  • A Painful Condition That Affects The Nerves In The Legs And Arms Called Peripheral Neuropathy
  • A Type Of Stomach Irritation Called Gastritis
  • Abnormal Color Of Urine
  • Abnormal Dreams
  • Abnormal Muscle Movements
  • Agitation
  • Anxious Feelings
  • Backache
  • Blurred Vision
  • Confusion
  • Decreased Appetite
  • Depression
  • Diarrhea
  • Dizziness
  • Drowsiness
  • Dry Mouth
  • Excessive Sweating
  • Fluid Retention In The Legs, Feet, Arms Or Hands
  • Gas
  • Generalized Weakness
  • Indigestion
  • Large Purple Or Brown Skin Blotches
  • Low Energy
  • Muscle Twitching
  • Taste Impairment
  • Temporary Redness Of Face And Neck
  • Trouble Breathing
  • Vomiting

RARE side effects


If experienced, these tend to have a Severe expression

  • A Condition Where There Is Formation Of Fibrous Tissue In The Lung Called Pulmonary Fibrosis
  • A Condition With Muscle Tissue Breakdown Called Rhabdomyolysis
  • A Heart Attack
  • A High Alanine Transaminase Level
  • A High Aspartate Transaminase Level
  • A Sudden Onset Of Sleep
  • A Type Of Blood Disorder Where The Red Blood Cells Burst Called Hemolytic Anemia
  • Abnormal Heart Rhythm
  • Abnormal Liver Function Tests
  • Accidental Falls
  • Aggressive Behavior
  • An Inability To Control Impulsive Behavior
  • An Ulcer Of The Duodenum
  • Anemia
  • Confusion
  • Decreased Blood Platelets
  • Delirium
  • Escape Of Fluid Into The Lungs
  • Extrapyramidal Disease, A Type Of Movement Disorder
  • Fever
  • High Amount Of Bilirubin In The Blood
  • High Blood Pressure
  • Iga Vasculitis
  • Increased Pressure In The Eye
  • Inflammation Of The Large Intestine
  • Inflammation Of The Liver Called Hepatitis
  • Inflammation Of The Skin With Blisters
  • Low Levels Of White Blood Cells
  • Mental Problems From Taking The Drug
  • Mental Status Changes
  • Neuroleptic Malignant Syndrome, A Reaction Characterized By Fever, Muscle Rigidity And Confusion
  • Painful And Involuntary Movement Of The Eyes Called Oculogyric Crisis
  • Paranoia
  • Priapism, A Prolonged Erection Of The Penis
  • Rapid Deep Breathing
  • Retroperitoneal Fibrosis
  • Suicidal Behavior
  • Suicidal Thoughts
  • Very Low Levels Of Granulocytes, A Type Of White Blood Cell
  • X-Ray Results Showing Lung Tissue Changes

If experienced, these tend to have a Less Severe expression

  • A Feeling Of General Discomfort Called Malaise
  • A Sore Throat
  • A Sudden Onset Of Sleep
  • An Extreme Sense Of Wellbeing Called Euphoria
  • An Inability To Completely Empty The Bladder
  • An Inability To Control Impulsive Behavior
  • An Increased Interest In Having Sexual Intercourse
  • Cough
  • Difficulty Swallowing
  • Double Vision
  • Drowsiness
  • Drug-Induced Hot Flashes
  • Excessive Saliva Production
  • Excessive Sweating
  • Fainting
  • Gas
  • Grinding Of The Teeth
  • Hair Loss
  • Hallucinations
  • Hiccups
  • Hoarseness
  • Inflammation Of A Vein
  • Intense Abdominal Pain
  • Involuntary Leakage Of Urine
  • Irritation Of The Stomach Or Intestines
  • Leg Pain
  • Lockjaw
  • Memory Loss
  • Nervousness
  • Numbness
  • Poisoning Caused By Anticholinergic Medication
  • Taste Impairment
  • Visible Water Retention
  • Weight Gain
  • Weight Loss

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.