Lansoprazole-Naproxen Combination Package Side Effects by Likelihood and Severity

COMMON side effects


If experienced, these tend to have a Severe expression

  • A Skin Rash
  • Abnormal Liver Function Tests
  • Hives
  • Ringing In The Ears
  • Water Retention

If experienced, these tend to have a Less Severe expression

  • A Common Cold
  • A Skin Rash
  • Constipation
  • Diarrhea
  • Dizziness
  • Drowsiness
  • Headache
  • Heartburn
  • Intense Abdominal Pain
  • Itching
  • Nausea
  • Visible Water Retention

INFREQUENT side effects


If experienced, these tend to have a Severe expression

  • A Change In Vision
  • Bleeding
  • Blurred Vision
  • Bruising
  • Bruising Under The Skin
  • Excessive Thirst
  • Large Purple Or Brown Skin Blotches

If experienced, these tend to have a Less Severe expression

  • Changes In Appetite
  • Cramps
  • Diarrhea
  • Excessive Sweating
  • Headache
  • Hearing Loss
  • Heart Throbbing Or Pounding
  • Indigestion
  • Joint Pain
  • Pain In The Muscles Or Bones
  • Pain In The Oropharynx
  • Sensation Of Spinning Or Whirling
  • Upper Abdominal Pain

RARE side effects


If experienced, these tend to have a Severe expression

  • A Blood Clot
  • A Broken Bone
  • A Condition Where There Is Formation Of Fibrous Tissue In The Lung Called Pulmonary Fibrosis
  • A Condition With Low Thyroid Hormone Levels
  • A Condition With Symptoms That Resemble Lupus
  • A Feeling Of Throat Tightness
  • A Heart Attack
  • A Respiratory Illness Called Loffler Syndrome
  • A Rupture In The Wall Of The Stomach Or Intestine
  • A Significant Type Of Allergic Reaction Called Anaphylaxis
  • A Skin Disorder With Blistering And Peeling Skin Called Stevens-Johnson Syndrome
  • A Skin Disorder With Blistering And Peeling Skin Called Toxic Epidermal Necrolysis
  • A Stomach Ulcer
  • A Stroke
  • A Systemic Inflammatory Response Called Sepsis Due To An Infection With Bacteria
  • A Type Of Allergic Reaction Called Angioedema
  • A Type Of Blood Disorder Where The Red Blood Cells Burst Called Hemolytic Anemia
  • A Type Of Blood Disorder With A Decrease In All Types Of Blood Cells Called Pancytopenia
  • A Type Of Kidney Inflammation Called Interstitial Nephritis
  • A Type Of Significant Allergic Skin Reaction Called DRESS Syndrome
  • A Type Of Skin Disorder Called Acute Generalized Exanthematous Pustulosis
  • A Yellowing Of The Eyes Or Skin From Buildup Of Bilirubin Called Jaundice
  • Abnormal Heart Rhythm
  • Abnormal Liver Function Tests
  • Acquired Hemolytic Anemia, An Anemia Due To Destruction Of Red Cells
  • Acute Inflammation Of The Pancreas
  • Acute Kidney Failure
  • Allergic Reaction Causing Inflammation Of Blood Vessels
  • An Ulcer From Too Much Stomach Acid
  • Anemia
  • Angina, A Type Of Chest Pain
  • Bleeding Of The Stomach Or Intestines
  • Blockage Of The Stomach Or Intestine
  • Blood Coming From Anus
  • Bloody Urine
  • Bloody Vomit
  • Bronchospastic Lung Disease
  • Chest Tightness
  • Chronic Heart Failure
  • Clouding Of The Lens Of The Eye Called Cataracts
  • Coma
  • Confusion
  • Corneal Opacity, A Scarring Disorder That Results In Clouding Of The Cornea Of The Eye
  • Decreased Blood Platelets
  • Decreased Kidney Function
  • Decreased Lung Function
  • Depression
  • Diarrhea From An Infection With Clostridium Difficile Bacteria
  • Elevation Of Proteins In The Urine
  • Erythema Multiforme, A Type Of Allergic Skin Reaction
  • Excess Urination
  • Fainting
  • Fast Heartbeat
  • Fever
  • Fluid In The Lungs
  • Gallstones
  • Glaucoma, An Increased Pressure In The Eye
  • Glomerulonephritis, A Condition That Affects The Kidneys
  • Hearing Loss
  • Heart Failure
  • High Blood Pressure
  • High Blood Sugar
  • High Levels Of Potassium In The Blood
  • Increased Eosinophils In The Blood
  • Inflammation Of The Bladder
  • Inflammation Of The Blood Vessels
  • Inflammation Of The Gallbladder
  • Inflammation Of The Large Intestine
  • Inflammation Of The Liver Called Hepatitis
  • Inflammation Of The Skin Due To An Allergy
  • Itching
  • Kidney Failure
  • Kidney Stones
  • Liver Failure
  • Low Amount Of Calcium In The Blood
  • Low Amount Of Potassium In The Blood
  • Low Amount Of Sodium In The Blood
  • Low Blood Counts Due To Bone Marrow Failure
  • Low Blood Pressure
  • Low Blood Sugar
  • Low Levels Of A Type Of White Blood Cell Called Neutrophils
  • Low Levels Of White Blood Cells
  • Low Platelet Count And Bleeding From Immune Response
  • Meningitis Not Due To An Infection
  • Muscle Pain
  • Nephrotic Syndrome, A Type Of Kidney Disorder
  • Pneumonia
  • Pneumonia With High Amount Of Eosinophil White Blood Cells
  • Renal Papillary Necrosis
  • Renal Tubular Necrosis, A Kidney Disorder
  • Seizures
  • Skin Rash With Sloughing
  • Slow Heartbeat
  • Stomach Or Intestinal Ulcer
  • Subacute Cutaneous Lupus Erythematosus
  • Sudden Blindness And Pain Upon Moving The Eye
  • Swollen Lymph Nodes
  • Systemic Lupus Erythematosus, An Autoimmune Disease
  • Throat Swelling
  • Thrombotic Thrombocytopenic Purpura, A Type Of Blood Disorder
  • Trouble Breathing
  • Very Low Levels Of Granulocytes, A Type Of White Blood Cell
  • Wheezing

If experienced, these tend to have a Less Severe expression

  • A Change In Voice
  • A Distorted Sense Of Smell Called Parosmia
  • A Feeling Of Pins And Needles On Skin
  • A Hairy Tongue
  • A Migraine Headache
  • A Painful, Red Or Swollen Tongue
  • A Problem With Menstrual Periods
  • A Type Of Speech Disorder Called Dysarthria
  • A Type Of Stomach Irritation Called Gastritis
  • Abdominal Bloating
  • Acne
  • Altered Interest In Having Sexual Intercourse
  • An Inability To Completely Empty The Bladder
  • An Infection Due To The Fungus Candida
  • An Infection Of The Mouth, Skin, Nails Or Vagina Due To Candida Fungus
  • Anemia
  • Anxious Feelings
  • Black Tarry Stools
  • Blistering Of The Skin
  • Burping
  • Changes In Appetite
  • Changes In The Visual Field
  • Chills
  • Cough
  • Decreased Urine Production
  • Depression
  • Difficult Or Painful Urination
  • Difficulty Concentrating
  • Difficulty Sleeping
  • Drowsiness
  • Dry Mouth
  • Enlarged Breasts
  • Erythema Nodosum, A Skin Condition With Red And Painful Nodules
  • Erythema Or Redness Of Skin Or Mucous Membrane
  • Fainting
  • Fast Heartbeat
  • Fever
  • Flu-Like Symptoms
  • Gas
  • Generalized Weakness
  • Hair Loss
  • Hallucinations
  • Heart Throbbing Or Pounding
  • Hives
  • Inadequate Vitamin B12
  • Increased Sensitivity Of The Skin To The Sun
  • Ineffective Painful Straining Of Stool Or Urine
  • Inflammation Of The Esophagus
  • Inflammation Of The Large Intestine
  • Inflammation Of The Sac Surrounding The Joint - Bursitis
  • Inflammation Of The Tonsils
  • Low Amount Of Magnesium In The Blood
  • Low Energy
  • Muscle Inflammation
  • Muscle Pain
  • Muscle Tremors
  • Muscle Weakness
  • Nervousness
  • Non-Cancerous Growths In The Stomach Called Benign Fundic Gland Polyposis
  • Nosebleed
  • Optic Disk Edema
  • Pain
  • Pain With Menstruation
  • Pain With Sexual Intercourse
  • Pink Eye
  • Puffy Face From Water Retention
  • Restless Legs Syndrome, An Extreme Discomfort In The Calf Muscles When Sitting Or Lying Down
  • Ringing In The Ears
  • Sensation Of Spinning Or Whirling
  • Skin Disease Characterized By Swollen Itching Lesions
  • Stomatitis, A Condition With Painful Swelling And Sores Inside The Mouth
  • Swelling Inside The Mouth
  • Swollen Lymph Nodes
  • Taste Impairment
  • Visible Water Retention
  • Vomiting
  • Weight Gain
  • Weight Loss
  • Widening Of Blood Vessels

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.