Symbyax Side Effects by Likelihood and Severity

COMMON side effects


If experienced, these tend to have a Severe expression

  • A Feeling Of Restlessness With Inability To Sit Still
  • A Type Of Movement Disorder Called Parkinsonism
  • Personality Disorders

If experienced, these tend to have a Less Severe expression

  • A Change In The Ability To Pay Attention
  • A High Prolactin Level
  • A Skin Rash
  • A Stuffy And Runny Nose
  • Abnormal Dreams
  • Anxious Feelings
  • Backache
  • Constipation
  • Decreased Appetite
  • Diarrhea
  • Difficulty Sleeping
  • Dizziness
  • Drowsiness
  • Dry Mouth
  • Excessive Sweating
  • Flu-Like Symptoms
  • Generalized Weakness
  • Headache
  • High Amount Of Triglyceride In The Blood
  • Increased Hunger
  • Indigestion
  • Inducing Of A Relaxed Easy State
  • Inflammation Of The Tissue Lining The Sinuses
  • Low Energy
  • Muscle Tremors
  • Nausea
  • Nervousness
  • Orthostatic Hypotension, A Form Of Low Blood Pressure
  • Problems With Ejaculation
  • The Inability To Have An Erection
  • Throat Irritation
  • Toxic Amblyopia, A Loss Of Vision
  • Weight Gain
  • Widening Of Blood Vessels
  • Yawning

INFREQUENT side effects


If experienced, these tend to have a Severe expression

  • An Extreme Sense Of Wellbeing Called Euphoria
  • Chest Pain
  • Extrapyramidal Disease, A Type Of Movement Disorder
  • Fever
  • Fluid Retention In The Legs, Feet, Arms Or Hands
  • High Blood Pressure
  • Memory Loss
  • Mental Status Changes
  • Tardive Dyskinesia, A Disorder Characterized By Involuntary Movements Of The Face, Mouth And Tongue

If experienced, these tend to have a Less Severe expression

  • A Change In Vision
  • A Feeling Of Pins And Needles On Skin
  • A Sleep Disorder
  • A Type Of Speech Disorder Called Dysarthria
  • Abnormal Heart Rhythm
  • Abnormal Liver Function Tests
  • Abnormal Manner Of Walking
  • Abnormal Sexual Function
  • Agitation
  • Altered Interest In Having Sexual Intercourse
  • An Abnormal Increase In Muscle Tone
  • An Increased Need To Urinate Often
  • Bruising Under The Skin
  • Chest Pain
  • Chills
  • Chills
  • Confusion
  • Constipation
  • Cough
  • Deep Sleep Or Sleep For Long Periods
  • Difficulty Sleeping
  • Excessive Saliva Production
  • Excessive Thirst
  • Fast Heartbeat
  • Fever
  • Gas
  • Hair Loss
  • Heart Throbbing Or Pounding
  • High Blood Pressure
  • Hives
  • Hyperactive Behavior
  • Indigestion
  • Involuntary Leakage Of Urine
  • Itching
  • Joint Pain
  • Low Blood Pressure
  • Muscle Stiffness
  • Nausea
  • Nervousness
  • Pain In The Arms Or Legs
  • Ringing In The Ears
  • Stomach Cramps
  • Taste Impairment
  • The Inability To Have An Erection
  • Throat Irritation
  • Urinary Tract Infection
  • Visible Water Retention
  • Vomiting
  • Weight Loss

RARE side effects


If experienced, these tend to have a Severe expression

  • A Blockage Of The Bile Duct That Resulting In High Bilirubin Levels
  • A Change In Vision
  • A Clot In The Lung
  • A Complication Of Diabetes With High Blood Ketone Levels Called Diabetic Ketoacidosis
  • A Condition With Muscle Tissue Breakdown Called Rhabdomyolysis
  • A Form Of Mania That Has A Lower Severity Of Symptoms
  • A Problem With Menstrual Periods
  • A Serum Sickness Reaction
  • A Significant Type Of Allergic Reaction Called Anaphylaxis
  • A Skin Disorder With Blistering And Peeling Skin Called Stevens-Johnson Syndrome
  • A Skin Rash
  • A Spasm Of The Larynx
  • A Stroke
  • A Type Of Allergic Reaction Called Angioedema
  • A Type Of Blood Disorder With A Decrease In All Types Of Blood Cells Called Pancytopenia
  • A Type Of Significant Allergic Skin Reaction Called DRESS Syndrome
  • A Yellowing Of The Eyes Or Skin From Buildup Of Bilirubin Called Jaundice
  • Abnormal Liver Function Tests
  • Abnormal Muscle Movements
  • Accidental Falls
  • Acquired Hemolytic Anemia, An Anemia Due To Destruction Of Red Cells
  • An Inability To Completely Empty The Bladder
  • An Increased Risk Of Bleeding
  • Atrial Fibrillation
  • Bleeding
  • Bleeding Of The Stomach Or Intestines
  • Blocked Bowels With Decreased Peristaltic Movement
  • Bronchospastic Lung Disease
  • Damage To The Liver And Inflammation
  • Decreased Blood Platelets
  • Diabetes
  • Difficulty Swallowing
  • Disturbance In The Ability Of The Eye To Focus
  • Enlarged Fatty Liver
  • Erythema Multiforme, A Type Of Allergic Skin Reaction
  • Erythema Nodosum, A Skin Condition With Red And Painful Nodules
  • Excessive Fat In The Blood
  • Heat Stroke
  • High Amount Of Bilirubin In The Blood
  • High Blood Sugar
  • Hyperosmolar Hyperglycemic State
  • Increased Eosinophils In The Blood
  • Inflammation Of The Liver Called Hepatitis
  • Inflammation Of The Liver With Stoppage Of Bile Flow
  • Kidney Failure
  • Large Purple Or Brown Skin Blotches
  • Liver Failure
  • Low Amount Of Sodium In The Blood
  • Low Blood Counts Due To Bone Marrow Failure
  • Low Levels Of A Type Of White Blood Cell Called Neutrophils
  • Low Levels Of White Blood Cells
  • Manic Behavior
  • Neuroleptic Malignant Syndrome, A Reaction Characterized By Fever, Muscle Rigidity And Confusion
  • Obstruction Of A Blood Vessel By A Blood Clot
  • Osteoporosis, A Condition Of Weak Bones
  • Painful And Involuntary Movement Of The Eyes Called Oculogyric Crisis
  • Pancreatitis
  • Pneumonia With High Amount Of Eosinophil White Blood Cells
  • Priapism, A Prolonged Erection Of The Penis
  • Problems With Food Passing Through The Esophagus
  • Prolonged QT Interval On EKG
  • Puffy Face From Water Retention
  • Pulmonary Hypertension
  • Secondary Angle-Closure Glaucoma, A Type Of Eye Disorder
  • Seizures
  • Serotonin Syndrome, A Type Of Disorder With High Serotonin Levels
  • Skin Rash With Sloughing
  • Sleep Apnea
  • Stomach Or Intestinal Ulcer
  • Sudden Blindness And Pain Upon Moving The Eye
  • Suicidal Thoughts
  • Swollen Lymph Nodes
  • Thrombotic Thrombocytopenic Purpura, A Type Of Blood Disorder
  • Torsades De Pointes, A Type Of Abnormal Heart Rhythm
  • Trouble Breathing
  • Very Low Levels Of Granulocytes, A Type Of White Blood Cell
  • Vocal Cord Swelling

If experienced, these tend to have a Less Severe expression

  • A High Prolactin Level
  • A Type Of Abnormal Movement Disorder Called Dyskinesia
  • A Type Of Stomach Irritation Called Gastritis
  • Abnormal Bleeding From The Uterus
  • Accidental Falls
  • Altered Interest In Having Sexual Intercourse
  • An Increased Need To Urinate Often
  • Bleeding Not Related To Menstrual Period
  • Breast Pain
  • Breastmilk Production Not Associated With Childbirth Or Nursing
  • Bruising Under The Skin
  • Bulging Of The Eyes
  • Clouding Of The Lens Of The Eye Called Cataracts
  • Confusion
  • Depersonalization, A Disconnection Of One's Own Sense Of Reality Or Identity
  • Difficult Or Painful Urination
  • Dilated Pupils
  • Enlarged Breasts
  • Grinding Of The Teeth
  • Hair Loss
  • Hives
  • Increased Sensitivity Of The Skin To The Sun
  • Inflammation Of The Lining Of The Stomach And Intestines
  • Inflammation Of The Skin Due To An Allergy
  • Itching
  • Loss Of Muscle Coordination
  • Low Blood Pressure
  • Low Blood Sugar
  • Memory Loss
  • Mood Changes
  • Nosebleed
  • Orgasm Problems
  • Poisoning Caused By Anticholinergic Medication
  • Restless Legs Syndrome, An Extreme Discomfort In The Calf Muscles When Sitting Or Lying Down
  • Small Reddish-Purplish Pin-Point Sized Spots On Skin
  • Stuttering
  • Vomiting
  • Widening Of Blood Vessels

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.