Who should not take Amitriptyline HCL?

The following conditions are contraindicated with this drug. Check with your physician if you have any of the following:


  • overactive thyroid gland
  • suicidal thoughts
  • wide-angle glaucoma
  • heart attack within the last 30 days
  • paralysis of the intestines
  • an inability to completely empty the bladder
  • CYP2D6 poor metabolizer
  • manic-depression
  • closed angle glaucoma
  • abnormal heart rhythm
  • liver problems
  • seizures
  • chronic idiopathic constipation
  • orthostatic hypotension
  • a form of low blood pressure
  • enlarged prostate
  • alcohol use disorder
  • coronary artery disease


  • Tricyclic Antidepressants and Tricyclic Compounds

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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.