Amitriptyline HCL Side Effects by Likelihood and Severity

COMMON side effects


If experienced, these tend to have a Less Severe expression

  • Dizziness
  • Drowsiness
  • Dry Mouth
  • Headache
  • Increased Hunger
  • Weight Gain

INFREQUENT side effects


If experienced, these tend to have a Severe expression

  • Abnormal Heart Rhythm
  • An Inability To Completely Empty The Bladder
  • Low Blood Pressure
  • Slow Heartbeat

If experienced, these tend to have a Less Severe expression

  • Abnormal Sexual Function
  • Altered Interest In Having Sexual Intercourse
  • Blurred Vision
  • Confusion
  • Constipation
  • Diarrhea
  • Difficulty Concentrating
  • Difficulty Sleeping
  • Excessive Sweating
  • Heartburn
  • Low Energy
  • Muscle Tremors
  • Nervousness
  • Over Excitement
  • Taste Impairment
  • The Inability To Have An Erection
  • Vomiting

RARE side effects


If experienced, these tend to have a Severe expression

  • A Disorder With Excess Antidiuretic Hormone Called Syndrome Of Inappropriate Antidiuretic Hormone
  • A Heart Attack
  • A Stroke
  • A Type Of Allergic Reaction Called Angioedema
  • A Type Of Slowed Heart Rhythm Disorder Called Heart Block
  • Abnormal Heart Electrical Signals
  • Abnormal Liver Function Tests
  • Accidental Falls
  • Decreased Blood Platelets
  • Extrapyramidal Disease, A Type Of Movement Disorder
  • Fast Heartbeat
  • Hallucinations
  • Increased Eosinophils In The Blood
  • Increased Pressure In The Eye
  • Increased Sensitivity Of The Skin To The Sun
  • Inflammation Of The Liver Called Hepatitis
  • Large Purple Or Brown Skin Blotches
  • Low Levels Of White Blood Cells
  • Mental Problems From Taking The Drug
  • Prolonged QT Interval On EKG
  • Rapid Ventricular Heartbeat
  • Secondary Angle-Closure Glaucoma, A Type Of Eye Disorder
  • Seizures
  • Serotonin Syndrome, A Type Of Disorder With High Serotonin Levels
  • Sinus Tachycardia, A Type Of Fast Heart Rate
  • Slurred Speech
  • Suicidal Thoughts
  • Swelling Of The Tongue
  • Tardive Dyskinesia, A Disorder Characterized By Involuntary Movements Of The Face, Mouth And Tongue
  • Ventricular Fibrillation, A Heart Rhythm Disorder
  • Very Low Levels Of Granulocytes, A Type Of White Blood Cell

If experienced, these tend to have a Less Severe expression

  • A Discolored Tongue
  • A Feeling Of Pins And Needles On Skin
  • A Feeling Of Restlessness With Inability To Sit Still
  • A Form Of Mania That Has A Lower Severity Of Symptoms
  • A Painful Condition That Affects The Nerves In The Legs And Arms Called Peripheral Neuropathy
  • A Skin Rash
  • A Type Of Speech Disorder Called Dysarthria
  • Aggressive Behavior
  • Agitation
  • An Inability To Control Impulsive Behavior
  • Anxious Feelings
  • Breastmilk Production Not Associated With Childbirth Or Nursing
  • Decreased Appetite
  • Delusions
  • Dilated Pupils
  • Disturbance In The Ability Of The Eye To Focus
  • Enlarged Breasts
  • Fainting
  • Feelings Of Hostility
  • Hair Loss
  • Heart Throbbing Or Pounding
  • High Blood Pressure
  • High Blood Sugar
  • Hives
  • Inflammation Of The Parotid Gland
  • Irritability
  • Itching
  • Loss Of Muscle Coordination
  • Low Blood Sugar
  • Manic Behavior
  • Nausea
  • Nightmares
  • Puffy Face From Water Retention
  • Ringing In The Ears
  • Stomatitis, A Condition With Painful Swelling And Sores Inside The Mouth
  • Swelling Of The Testicles
  • Weight Loss

Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.

CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.