Tuberculin Testing/Live Vaccines Interactions
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Medical warning:
Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
You may receive the test for tuberculosis (TB) within one day of receiving live vaccines. However, if the TB test is not done within one day, it should be deferred until at least 4-6 weeks after the live vaccine. Your immune system may not react to the TB test if it is done sooner.
What might happen:
The results of your TB test could be wrong.
What you should do about this interaction:
Make sure your healthcare professionals (e.g. doctor or pharmacist) know about any vaccinations you have recently received. Discuss the timing of your vaccines and your TB test with your healthcare provider. You may need to reschedule your TB test or repeat the TB test in order to make sure it is accurate.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
- 1.Centers for Disease Control and Prevention. General Recommendations on Immunization. Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR. Available at: https://www.cdc.gov/vaccines/hcp/acip-recs/general-recs/index.html February 17, 2022;60(RR No.
- 2):1-68.
- 3.Tubersol (tuberculin purified protein derivative) US prescribing information. Sanofi Pasteur Limited February, 2013.
- 4.Aplisol (tuberculin purified protein derivative) US prescribing information. JHP Pharmaceuticals, LLC November, 2013.
- 5.Brickman HF, Beaudry PH, Marks MI. The timing of tuberculin tests in relation to immunization with live viral vaccines. Pediatrics 1975 Mar; 55(3):392-6.
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.