Slt HMG-CoA Reductase Inhibitors/Ketoconazole; Posaconazole Interactions
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Very Serious. These medicines may interact and cause very harmful effects and are usually not taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
When these two medicines are taken together, your body may not process your cholesterol medicine properly.
What might happen:
Your blood levels of your cholesterol medicine may increase and cause possible toxic side effects.
What you should do about this interaction:
Let your healthcare professionals (e.g. doctor or pharmacist) know right away that you are taking these medicines together. You may need to take a different cholesterol medicine.Tell your doctor right away if you experience muscle pain, tenderness, or weakness; unexplained tiredness; or discolored urine.Your healthcare professionals (e.g. doctor or pharmacist) may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
- 1.Nizoral (ketoconazole oral) US prescribing information. Janssen Pharmaceuticals February, 2014.
- 2.Noxafil (posaconazole) UK summary of product characteristics. Schering-Plough Ltd. January, 2022.
- 3.Noxafil (posaconazole) US prescribing information. Merck & Co. Inc January, 2022.
- 4.Baycol (cerivastatin) US prescribing information. Bayer Corporation December, 2000.
- 5.Mevacor (lovastatin) US prescribing information. Merck & Co., Inc. February, 2014.
- 6.Zocor (simvastatin) US prescribing information. Merck & Co., Inc. May, 2022.
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CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.